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Protein Alignment wtrw and Trpv1

DIOPT Version :9

Sequence 1:	NP_731193.1	Gene:	wtrw / 40931	FlyBaseID:	FBgn0260005	Length:	986	Species:	Drosophila melanogaster
Sequence 2:	NP_001001445.1	Gene:	Trpv1 / 193034	MGIID:	1341787	Length:	839	Species:	Mus musculus

Alignment Length:	819	Identity:	160/819 - (19%)
Similarity:	277/819 - (33%)	Gaps:	254/819 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 LVAKGLNVNLQSKCYTPLHCA-AFGNAAEAAKLLINNGADISKDTSKPNC--------------- 250
            |..||     .|:..:|:.|. ..|..|....:.:::...:.:....|.|
Mouse    49 LFGKG-----DSEEASPMDCPYEEGGLASCPIITVSSVVTLQRSVDGPTCLRQTSQDSVSTGVET 108

  Fly   251 ------EESLLHCAVRSNA--LECLQIFI---------AEGADVNSLKP----------NGTN-A 287
                  ..|:.....:||.  ||.|..|:         :|..|..:.|.          ||.| .
Mouse   109 PPRLYDRRSIFDAVAQSNCQELESLLSFLQKSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQNDT 173

  Fly   288 IHLAADLG-NIQCLEALLNAPNADANVRICIREKESTALHLAADEGNVECVDLLLAKGADA---- 347
            |.|..|:. ....|:..:||...|:..      |..||||:|.:..|:..|.||:..|||.
Mouse   174 IALLLDIARKTDSLKQFVNASYTDSYY------KGQTALHIAIERRNMALVTLLVENGADVQAAA 232

  Fly   348 ------KLKNHRGF----TPLHLAARTSSLDCVESLLRNG--NADANAEDFDHRTPLHAAVGKSE 400
                  |.|...||    .||.|||.|:.|..|:.||:|.  .||.:|.|....|.|||.|..::
Mouse   233 NGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVAD 297

  Fly   401 NAYD-------IMETLIQWGANV----------NHKDIYGFTALHLAALDGLVQCVEMLI---FH 445
            |..|       :...::..||.:          |.|   |.|.|.|||..|.:..:..::   .|
Mouse   298 NTADNTKFVTNMYNEILILGAKLHPTLKLEELTNKK---GLTPLALAASSGKIGVLAYILQREIH 359

  Fly   446 GADVTTKSKKGTSALNVITRKTPASVAMIRQKLDAAITLHHSQ-------DPVNREVELELDFRQ 503
            ..:....|:|.|                     :.|....||.       |...:...||:
Mouse   360 EPECRHLSRKFT---------------------EWAYGPVHSSLYDLSCIDTCEKNSVLEV---- 399

  Fly   504 LLQHCHPREISYLNTFVDEGQKEILEHPLCSSFLYIKWGKI--RKYYIGRLIFCFSFVLFLTLYV 566
                     |:|.::........:|..|| :..|..||.:.  |.:|....::|...::|
Mouse   400 ---------IAYSSSETPNRHDMLLVEPL-NRLLQDKWDRFVKRIFYFNFFVYCLYMIIF----- 449

  Fly   567 LTALAHNCYNGSKNDNTTIPAQELCQKQSILGDMLRNNPFVMEMQWWVLVAITIVEIF------- 624
            .||..:....|       :|..:|   .:.:||..|....::.:...|......::.|
Mouse   450 TTAAYYRPVEG-------LPPYKL---NNTVGDYFRVTGEILSVSGGVYFFFRGIQYFLQRRPSL 504

  Fly   625 RKLYGITGYSSFRHYVTQVENIMEWFVITSVFVISYIYTNKTYTFQNHIGAFAVLLGWTNLMLMI 689
            :.|: :..||....:|..:      |::.|  |:.|....|.|....   .|::.:||||::...
Mouse   505 KSLF-VDSYSEILFFVQSL------FMLVS--VVLYFSHRKEYVASM---VFSLAMGWTNMLYYT 557

  Fly   690 GQLPVFDVYVAMYTR-VQGEFAKLFMAYSCMLIGFTISFCVIFPS-------------------- 733
            .......:|..|..: :..:..:....|...|.||:.:...:...
Mouse   558 RGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLIEDGKNNSLPVESPPHKCRGSAC 622

  Fly   734 --SSSFANPFMGFITVLVMMIGEQDLSLLINDPEGKDPPFLLEVSAQITFVLFLL----FVTIIL 792
              .:|:.:.:...:.:....||..||.            |......:..|::.||    ...|:|
Mouse   623 RPGNSYNSLYSTCLELFKFTIGMGDLE------------FTENYDFKAVFIILLLAYVILTYILL 675

  Fly   793 MNLLVGIAVHDIQGLKKTAGLSKLVRQTKLISYIESALFNGYLPTWLRNLLHYTALVSPQAYRVV 857
            :|:|:.:....:         :|:.:::|.|..::.|:               |.|.:.:::  :
Mouse   676 LNMLIALMGETV---------NKIAQESKNIWKLQRAI---------------TILDTEKSF--L 714

  Fly   858 LCVKPLNPSEKRLPREILMKAYEVGKMRKHFGHTISSKN 896
            .|::               ||:..||:.: .|.|...|:
Mouse   715 KCMR---------------KAFRSGKLLQ-VGFTPDGKD 737

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.