Protein Alignment wtrw and ANKRD54

DIOPT Version :10

• Sequence 1: NP_731193.1
• Gene: wtrw / 40931
• FlyBaseID: FBgn0260005
• Length: 986
• Species: Drosophila melanogaster
• Sequence 2: XP_011528179.1
• Gene: ANKRD54 / 129138
• HGNCID: 25185
• Length: 344
• Species: Homo sapiens
• Alignment Length: 178
• Identity: 40/178 - (22%)
• Similarity: 62/178 - (34%)
• Gaps: 61/178 - (34%)

  Fly   164 DLIESLLEAGADLHFCDQNGISALHLSAFSG-------------------------CLATLGLLV 203
            :.::.|||.|||....|..|.:|||.::.:|                         |..|:.|::
Human   124 ETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIGQEALPKSSVPGPQGFAHELCCSWTMVLIL 188

  Fly   204 AKGLNVNLQSKCYTPLHCAAFGNAAEAAKLLINNGADISKDTSKPNCEESLLHC-------AVRS 261
            ...:.       :...||.  ...|....|            |.|:|.|.:  |       :...
Human   189 TSEMG-------WGTRHCT--WRPAPTTFL------------SSPHCYEEV--CGFFPSLSSFSP 230

  Fly   262 NALECLQIFIAEGADVNSLKPNGTNAIHLAADL------GNIQCLEAL 303
            :..||....:..||.|::|...|...:|||...      |:.|||||:
Human   231 SPPECSPQLVPAGARVDALDRAGRTPLHLAKSKLNILQEGHAQCLEAV 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wtrw	NP_731193.1	ANK repeat	182..213	CDD:293786	8/55 (15%)
		ANKYR	196..482	CDD:440430	27/121 (22%)
		ANK repeat	215..242	CDD:293786	4/26 (15%)
		ANK repeat	250..281	CDD:293786	8/37 (22%)
		ANK repeat	283..317	CDD:293786	10/27 (37%)
		ANK repeat	323..351	CDD:293786
		ANK repeat	353..385	CDD:293786
		ANK repeat	387..420	CDD:293786
		ANK repeat	422..452	CDD:293786
		Ion_trans	613..812	CDD:459842
ANKRD54	XP_011528179.1	ANKYR	<118..>158	CDD:440430	12/33 (36%)