Protein Alignment wtrw and LOC1279693

DIOPT Version :10

• Sequence 1: NP_731193.1
• Gene: wtrw / 40931
• FlyBaseID: FBgn0260005
• Length: 986
• Species: Drosophila melanogaster
• Sequence 2: XP_061516912.1
• Gene: LOC1279693 / 1279693
• VectorBaseID: AGAMI1_000842
• Length: 1126
• Species: Anopheles gambiae
• Alignment Length: 1064
• Identity: 645/1064 - (60%)
• Similarity: 771/1064 - (72%)
• Gaps: 99/1064 - (9%)

  Fly     2 ENLGYKEGSTKPRRMTRSISVVTKTEVEQPLTENN------ANNRFKSIPPNLMVRWRNNTDAMI 60
            ||....|.|||...:..:||.|| ..:.:...:|:      .|..|.:         ..||:...
Mosquito    78 ENGPRNENSTKTANIQNNISDVT-AGIRRSSADNHNVSAATVNGSFTT---------TTNTNTKT 132

  Fly    61 EAQYPTAGE----------FEYMECGPSPPAESAPSMYDSFEEPTSELSVQICNDTLRISLIDQM 115
            .|.:...|:          :||||.|||||||.||::|||::|..||.|.|:|||.:||||.:||
Mosquito   133 TASHSGTGQPNGRKSHVDCYEYMEVGPSPPAEGAPNLYDSYDESYSESSAQLCNDIIRISLTEQM 197

  Fly   116 KSAAGRVKLFEDIE----------------QSNVVAEGIRTHFESAS------------KLEKNL 152
            :.|.|||.|.|..|                .:.:...|..|:..:.:            :||||:
Mosquito   198 RLAGGRVALLESFELDLTLDCAAVEHLLNGTATLATSGPATNTSTTTFPTNNSVCVGGQQLEKNI 262

  Fly   153 CYLWAAYLKRWDLIESLLEAGADLHFCDQNGISALHLSAFSGCLATLGLLVAKGLNVNLQSKCYT 217
            |:||||:|:::.|::..:..|||::|||.||::||||::||||......|:..||:||:|.|.||
Mosquito   263 CFLWAAFLRKFHLLDQCVRLGADINFCDSNGLTALHLASFSGCTECCAFLIQHGLDVNMQPKWYT 327

  Fly   218 PLHCAAFGNAAEAAKLLINNGADISKDTSKPNCEESLLHCAVRSNALECLQIFIAEGADVNSLKP 282
            |||||||||:...|:|||.|||.|...|:|.:||||||||||||||::||:.|||.|::||:|:.
Mosquito   328 PLHCAAFGNSLATAELLIKNGARIDVPTNKQHCEESLLHCAVRSNAIDCLRFFIAHGSNVNALER 392

  Fly   283 NGTNAIHLAADLGNIQCLEALLNAPNADANVRICIREKESTALHLAADEGNVECVDLLLAKGADA 347
            ||||.||||||||:.|||.|||..||||.|:||...:|:.|||||||||||::||..|||:|||.
Mosquito   393 NGTNPIHLAADLGHTQCLAALLECPNADPNIRIQQGDKQMTALHLAADEGNLDCVTQLLARGADV 457

  Fly   348 KLKNHRGFTPLHLAARTSSLDCVESLLRNGNADANAEDFDHRTPLHAAVGKSENAYDIMETLIQW 412
            :.:|||||||||||||:.|.||||:||:.|..|.|..|||.||||||||.||:.|.:::||||.|
Mosquito   458 RARNHRGFTPLHLAARSGSADCVEALLKLGGCDPNMADFDQRTPLHAAVSKSDTAVEMIETLIAW 522

  Fly   413 GANVNHKDIYGFTALHLAALDGLVQCVEMLIFHGADVTTKSKKGTSALNVITRKTPASVAMIRQK 477
            |||||.:|:||||||||||||.|..|||.|::||||||.||:|||||||:|:||||||:.:|:.|
Mosquito   523 GANVNQRDVYGFTALHLAALDALGPCVETLLYHGADVTMKSRKGTSALNIISRKTPASLGVIQCK 587

  Fly   478 LDAAITLHHSQDPVNREVELELDFRQLLQHCHPREISYLNTFVDEGQKEILEHPLCSSFLYIKWG 542
            |||||||.||||..:||||||||||.:|||||||||||||||||:||||.|:|||||:||||||.
Mosquito   588 LDAAITLTHSQDSSSREVELELDFRSILQHCHPREISYLNTFVDDGQKEFLQHPLCSAFLYIKWN 652

  Fly   543 KIRKYYIGRLIFCFSFVLFLTLYVLTALAHNCYNGSKNDNTTIPAQELCQKQSILGDMLRNNPFV 607
            |||||||.||:|||:||||||||||||||||||||||:...||..|||||||||.||||||||||
Mosquito   653 KIRKYYIARLLFCFTFVLFLTLYVLTALAHNCYNGSKDMKETIQEQELCQKQSIFGDMLRNNPFV 717

  Fly   608 MEMQWWVLVAITIVEIFRKLYGITGYSSFRHYVTQVENIMEWFVITSVFVISYIYTNKTYTFQNH 672
            :||||.||||||.:||.||:||||||:|.:|||||.||.:|||:|.||||||||||.:|||:|||
Mosquito   718 IEMQWMVLVAITAIEICRKIYGITGYTSLKHYVTQTENAIEWFIILSVFVISYIYTKRTYTWQNH 782

  Fly   673 IGAFAVLLGWTNLMLMIGQLPVFDVYVAMYTRVQGEFAKLFMAYSCMLIGFTISFCVIFPSSSSF 737
            :||||||||||||||||||||||..||||||:||.||||||||||||||||||||||||||||||
Mosquito   783 VGAFAVLLGWTNLMLMIGQLPVFGAYVAMYTKVQVEFAKLFMAYSCMLIGFTISFCVIFPSSSSF 847

  Fly   738 ANPFMGFITVLVMMIGEQDLSLLINDPEGKDPPFLLEVSAQITFVLFLLFVTIILMNLLVGIAVH 802
            ||||||||||||||.|||||.||||||:|||||||||:||||||||||||||:||||||:|||||
Mosquito   848 ANPFMGFITVLVMMTGEQDLELLINDPDGKDPPFLLEISAQITFVLFLLFVTVILMNLLIGIAVH 912

  Fly   803 DIQGLKKTAGLSKLVRQTKLISYIESALFNGYLPTWLRNLLHYTALVSPQAYRVVLCVKPLNPSE 867
            |||||||||||||||||||||||||||||||:||.||||||:||||||||||||||.||||||.|
Mosquito   913 DIQGLKKTAGLSKLVRQTKLISYIESALFNGWLPNWLRNLLYYTALVSPQAYRVVLSVKPLNPGE 977

  Fly   868 KRLPREILMKAYEVGKMRKHF-GHTISSKNSAENYLSYKNKY----------------------- 908
            .||||:|:|.||||.|.:||: ..:.|:.....:|...||..
Mosquito   978 TRLPRDIMMAAYEVAKQKKHYVRKSFSTLRRDVSYDPQKNALIVNGMQSKTYKRTDSSCNVSNCR 1042

  Fly   909 ----------NNNNGATT--GYVLPDSDPDAGQFTTLTTKIDDNADRIEFLTQEIQELKQALISQ 961
                      :.||..||  |||.     |......||.|:|::.|.|..:..||.||:..:...
Mosquito  1043 RAAHTGMGVASTNNDHTTKFGYVY-----DTPTLYGLTNKLDEHNDYIGNIATEIAELRSTIEEN 1102

  Fly   962 QQQASKVIDKLLIVISNQQKQNLR 985
            ||...:|::    ::|..|..|::
Mosquito  1103 QQMLRQVLE----LLSKSQTHNIQ 1122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wtrw	NP_731193.1	ANK repeat	182..213	CDD:293786	15/30 (50%)
		ANKYR	196..482	CDD:440430	188/285 (66%)
		ANK repeat	215..242	CDD:293786	18/26 (69%)
		ANK repeat	250..281	CDD:293786	22/30 (73%)
		ANK repeat	283..317	CDD:293786	25/33 (76%)
		ANK repeat	323..351	CDD:293786	19/27 (70%)
		ANK repeat	353..385	CDD:293786	21/31 (68%)
		ANK repeat	387..420	CDD:293786	22/32 (69%)
		ANK repeat	422..452	CDD:293786	23/29 (79%)
		Ion_trans	613..812	CDD:459842	171/198 (86%)
LOC1279693	XP_061516912.1	None