Protein Alignment ArgRS-m and MSR1

DIOPT Version :10

• Sequence 1: NP_649745.3
• Gene: ArgRS-m / 40929
• FlyBaseID: FBgn0037526
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_011959.1
• Gene: MSR1 / 856491
• SGDID: S000001133
• Length: 643
• Species: Saccharomyces cerevisiae
• Alignment Length: 526
• Identity: 193/526 - (36%)
• Similarity: 299/526 - (56%)
• Gaps: 50/526 - (9%)

  Fly   100 GRSAAKIEFQLQPQVFVEQ--LLQT--KEIALHPSPFA---AEH---IVVEYSSPNIAKPFHVGH 154
            |:..||..|.   |.|::|  |:|:  ..|.|....:.   :.|   :|||:||||||||||.||
Yeast   137 GKVCAKGPFL---QFFLDQRYLIQSTVPNILLQKGKYGQKKSRHQKKVVVEFSSPNIAKPFHAGH 198

  Fly   155 LRSTIIGNVLANLHEHLGYRTTRLNYLGDWGTQFGLLVLGVQLLNVSDKEMQLSPIETLYKSYVA 219
            |||||||..|:||:|.:|:..||:|||||||.|||||.:|.:... .:|.:|..||:.|:..||.
Yeast   199 LRSTIIGGFLSNLYEAMGWSVTRMNYLGDWGRQFGLLAVGFKRYG-DEKTLQKQPIQHLFDVYVK 262

  Fly   220 ANK--AAEQ-----RPEIAQQARDLFAALEGGTDKSMAKKWQQYRNYTIEDLSKVYNRLGVHFDS 277
            .|.  |.|:     :..|:.:||..|..||.| |::..|.|.::|:.:|....:.|:||.::||.
Yeast   263 INMDLAKEEINGNSKCGISGEARSFFKNLENG-DENAIKIWNRFRSLSIHHYIQTYSRLNINFDI 326

  Fly   278 YEWESQYSQQQIQDVLDKLRSAGLLQPEHDGREIVVVD--------GRRIPVIKSNGSTLYLARD 334
            :..|||.|::.:.:.||..|...|:: |.||  .:|:|        | |:.|.||:|:||||.||
Yeast   327 FSGESQVSKESMNEALDIFRKNNLVK-EIDG--ALVIDLTQWSKRLG-RVVVQKSDGTTLYLTRD 387

  Fly   335 IAALLERLSRFQFSRLLYVVDNGQADHFNALFKTTAALDDRLSLEQLQHVKFGRIYGMSTRQGKA 399
            :.|.:||.....|.:::||:.:.|..:.:..|.....::...: :.|||:.||.:.|||||:|..
Yeast   388 VGAAIERKKNLHFDKMVYVISSQQDLYMSQFFMILKKMNFEWA-KDLQHINFGMVQGMSTRKGNV 451

  Fly   400 IFLKDVLDEARD----IM-REKRNISATTRENYNLDDEHVCDILGVSAVLVNVLKQRRQRDHEFS 459
            :||..:||||||    || ..|..||...      :.:.|.|::||||:::..:|.:|..::||:
Yeast   452 VFLDTILDEARDKALQIMENNKMKISQVD------NPQRVADLIGVSAIIIQDMKSKRINNYEFN 510

  Fly   460 WQQALQVNGDTGIKLQYTHCRLHSLLDNFRDVDLDD-IKPDWKHFSTEPADALDLLYALARFDQS 523
            |.:.|...||||..|||||.||.||.....|...|. |..|:.:.: || ..::|:..||::...
Yeast   511 WNRMLSFEGDTGPYLQYTHSRLRSLERTSSDFTTDMLIHADFSNLN-EP-QLVELVRLLAQYPDV 573

  Fly   524 VWQSKEQLEACVLVNYLFGLCNATSQALKRLPVKQESSLEKQLQRLLLFHAAKKTLRHGMELLGL 588
            :.::.|..|...:|.|||.:|:..|...|::.|..:.: :..:.||.::.|:::.|.:.|.||||
Yeast   574 LRRAFETQEPATIVTYLFKVCHQVSSCYKKIWVSGKPA-DIAIPRLAVYSASRQVLHNAMSLLGL 637

  Fly   589 RPLNQM 594
            .|:::|
Yeast   638 VPVDRM 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ArgRS-m	NP_649745.3	ArgS	67..594	CDD:439789	192/524 (37%)
MSR1	NP_011959.1	argS	69..643	CDD:273085	192/524 (37%)