Protein Alignment CG2993 and Arrdc1

DIOPT Version :10

• Sequence 1: NP_001262348.1
• Gene: CG2993 / 40924
• FlyBaseID: FBgn0037521
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_038961503.1
• Gene: Arrdc1 / 366001
• RGDID: 1309961
• Length: 460
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 114/514 - (22%)
• Similarity: 186/514 - (36%)
• Gaps: 158/514 - (30%)

  Fly    14 QG--VYYAGQELSGVVDLSVDATKRIKGIHVTVSGYAKIRWIKKGYPRDSERAMCRAY---RSYL 73
            ||  ||..|:.|:|.|.|.:.|....:.|.||..|...:          |.:|...|:   .||.
  Rat    13 QGRVVYSPGEPLAGAVHLRLGAPLPFRAIRVTCMGSCGV----------SNKANDGAWVVEESYF 67

  Fly    74 SSRSYVLGSCANNSSIDWPAGEYSYTFHVILPDNLPTSFDGKYGQIHYEIITTIERAARHPKVFK 138
            :|..    |.|:..|:  |.||:::.|..:||...||||:|.:|:|.:::..:|: ..|..|..|
  Rat    68 NSSL----SLADKGSL--PPGEHNFPFQFLLPATAPTSFEGPFGKIVHQVRASID-TPRFSKDHK 125

  Fly   139 --LPFTVIQPLDLNADAIYRVPLEILDRKRFWSFCCPTGPLTVKFSTPYCGYAPGQKIHFVLYIN 201
              |.|.::.||:||:......|......|:|......||.:.:..||...||..||.:.....|.
  Rat   126 CSLVFYILSPLNLNSIPDIEQPNVASTTKKFSYKLVKTGSVVLTASTDLRGYVVGQVLRLQADIE 190

  Fly   202 NESSIDIIECEVKLKQEVSYESHDPQHEYRYDKHLIARKQFGNVLRWSRKVYRGYLDLPSIPPTS 266
            |:|..|.......|.|:|||::    ..:.||...||..:...|..|....::..:.:|::|.::
  Rat   191 NQSGKDTSPVVASLLQKVSYKA----KRWIYDVRTIAEVEGTGVKAWRHAQWQEQILVPALPQSA 251

  Fly   267 VKPTCP-ISVNYSIKIIVNP-----------------TEFHWKLK-----LKIPLTIGSIPIMDG 308
            : |.|. |.::|.:::...|                 ..|...:|     :.:||.:|:|.:...
  Rat   252 L-PGCSLIHIDYYLQVWCCPGLGGLRLGGLGLTLQYLRFFQVSMKAPEATVTLPLFVGNIAVNQT 315

  Fly   309 P--------------EALLRFNRQQQQHQVVSQNLQMSTQQRQRDRDRDRDMNVDRERDRDRDRD 359
            |              ..::.....|::.:.|:.....|                          |
  Rat   316 PLSPCPGPGSSPGLLSPVVPSAPPQEEAEAVASGPHFS--------------------------D 354

  Fly   360 RISASV----QQRRISSINNNNNNHGRLVGGLLPTNSNMNMITNVSPTPTSSTPS---------- 410
            .:|.|.    ||:.:|                  |......:|.:.|.....:|:
  Rat   355 PVSLSTKSHSQQQPLS------------------TTLGSVSVTTIEPCVQVGSPARHSLHPPLCI 401

  Fly   411 ---------------STPTTAALRPTAMPAILVTSDSDNPPDYIPM-----MPPSYEDA 449
                           ..|||:||       ||       ||:|...     .|||||.:
  Rat   402 SIGATVPYFAEGSGGPVPTTSAL-------IL-------PPEYSSWGYPYEAPPSYEQS 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2993	NP_001262348.1	Arrestin_N	5..150	CDD:451447	44/142 (31%)
		Arrestin_C	174..304	CDD:214976	35/152 (23%)
Arrdc1	XP_038961503.1	Arrestin_N	7..139	CDD:451447	44/142 (31%)
		Arrestin_C	162..310	CDD:460676	35/152 (23%)
		PHA03247	<311..449	CDD:223021	29/194 (15%)