Protein Alignment CG18268 and ARRDC1

DIOPT Version :10

• Sequence 1: NP_649739.1
• Gene: CG18268 / 40923
• FlyBaseID: FBgn0037520
• Length: 358
• Species: Drosophila melanogaster
• Sequence 2: XP_006717383.1
• Gene: ARRDC1 / 92714
• HGNCID: 28633
• Length: 466
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 47/239 - (19%)
• Similarity: 94/239 - (39%)
• Gaps: 57/239 - (23%)

  Fly    93 NEVLQL-ENGTFRLGD----FNFQLPENLPATCRLPFGNVEYVLKVVLE--RRGTHNKCFQQRLV 150
            |..|.| :.|:...|:    |.|.||...|.:...|||.:.:.::..:.  |....:||.....:
Human    75 NSSLSLADKGSLPAGEHSFPFQFLLPATAPTSFEGPFGKIVHQVRAAIHTPRFSKDHKCSLVFYI 139

  Fly   151 IRKC-------VELADL----KP--------------------QYMETANMGLTLPRSV--FVPG 182
            :...       :|.:.|    ||                    :.::|.::.||....:  :|.|
Human   140 LSPLNLNSIPDIEGSSLRTPAKPLPGPPPKQPNVASATKKFSYKLVKTGSVVLTASTDLRGYVVG 204

  Fly   183 QSVSY--EICSKDG--VQDFLTRLCKKISYTSQQPSAKTKNVTQVLSESSELNGNLRL----PLT 239
            |::..  ::.::.|  ....:..|.:|:||.:::.....:.:.:|  |.:.:....|.    .:.
Human   205 QALQLHADVENQSGKDTSPVVASLLQKVSYKAKRWIHDVRTIAEV--EGAGVKAWRRAQWHEQIL 267

  Fly   240 APIMSHS--DQLDPIQISYYIETFNSLNAP---IKVPIFVATVA 278
            .|.:..|  .....|.|.||::.  ||.||   :.:|:|:..:|
Human   268 VPALPQSALPGCSLIHIDYYLQV--SLKAPEATVTLPVFIGNIA 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18268	NP_649739.1	Arrestin_N	5..153	CDD:451447	16/66 (24%)
		Arrestin_C	172..279	CDD:460676	26/122 (21%)
ARRDC1	XP_006717383.1	Arrestin_N	<82..146	CDD:451447	13/63 (21%)
		Arrestin_C	186..308	CDD:460676	26/125 (21%)