DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18268 and Arrdc3

DIOPT Version :10

Sequence 1:NP_649739.1 Gene:CG18268 / 40923 FlyBaseID:FBgn0037520 Length:358 Species:Drosophila melanogaster
Sequence 2:NP_001007798.1 Gene:Arrdc3 / 309945 RGDID:1359478 Length:414 Species:Rattus norvegicus


Alignment Length:336 Identity:70/336 - (20%)
Similarity:132/336 - (39%) Gaps:81/336 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 IYYNGEQISGSLTVTVDGKKSFKLEGVSVTLHGVSTVHWRESLRGPPEIEHNDSTGNLECPKVDY 79
            :|.:|:.:||.:.:.|.|:  .:::.:.:...|.:.|.|.||........:..:    ...:|:|
  Rat    23 VYSSGDTVSGRVNLEVTGE--IRVKSLKIHARGHAKVRWTESRNAGSNTAYTQN----YTEEVEY 81

  Fly    80 NGSK----VHINETKKLNEVLQ-LENGTFRLGDFNFQLPENLPATCRLPF----GNVEYVLKVVL 135
            ...|    .|..:.....|... :.:|..... |:|:||:...||   .|    |:|.|.:|..|
  Rat    82 FNHKDILIGHERDDDNCEEGFSTIHSGRHEYA-FSFELPQTPLAT---SFEGRHGSVRYWVKAEL 142

  Fly   136 ERRGTHNKCFQQRLVIRKCVEL---ADLKPQ-----------YMETANMGLT--LPRSVFVPGQS 184
            .|........::...:.:.:::   :.|.||           :..:..:.|:  :.|..:.||:|
  Rat   143 HRPWLLPVKLKKEFTVFEHIDINTPSLLSPQAGTKEKTLCCWFCTSGPISLSAKIERKGYTPGES 207

  Fly   185 V----SYEICSKDGVQDFLTRLCKKISYTSQQPSAKTKNVTQVLSESSELNGNLR---------- 235
            :    ..|.||...|      :.|...|.:|...||.|     :.|..:|..|||          
  Rat   208 IQIFAEIENCSSRMV------VPKAAIYQTQAFYAKGK-----MKEVKQLVANLRGESLSSGKTE 261

  Fly   236 --------LPLTAPIMSHSDQLD--PIQISY----YIETFNSLNAPIKVPIFVATV-APPVNSQT 285
                    :|..:|.:     ||  .|::.|    |::...:::..:.:|:.:.|: ..|..|:|
  Rat   262 TWDGKLLKIPPVSPSI-----LDCSIIRVEYSLMVYVDIPGAMDLLLSLPLVIGTIPLHPFGSRT 321

  Fly   286 ES-SQLCFVNM 295
            .| |..|.:||
  Rat   322 SSVSSQCSMNM 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18268NP_649739.1 Arrestin_N 5..153 CDD:451447 30/146 (21%)
Arrestin_C 172..279 CDD:460676 29/137 (21%)
Arrdc3NP_001007798.1 Arrestin_N 22..165 CDD:425619 30/151 (20%)
Arrestin_C 187..314 CDD:214976 29/142 (20%)
PPxY motif 1. /evidence=ECO:0000305 346..349
PPxY motif 2. /evidence=ECO:0000305 391..394
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 393..414
Blue background indicates that the domain is not in the aligned region.

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