Protein Alignment CG18268 and ARRDC2

DIOPT Version :10

• Sequence 1: NP_649739.1
• Gene: CG18268 / 40923
• FlyBaseID: FBgn0037520
• Length: 358
• Species: Drosophila melanogaster
• Sequence 2: NP_056498.1
• Gene: ARRDC2 / 27106
• HGNCID: 25225
• Length: 407
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 61/319 - (19%)
• Similarity: 116/319 - (36%)
• Gaps: 71/319 - (22%)

  Fly    15 IYYNGEQISGSLTVTVDGKKSFKLEGVSVTLHGVSTVHWRESLRGPPEIEHNDSTGNLECPKVDY 79
            ::..|:.::|  .|.::...:.::..:.:...|.:.|||.||........:..|...    :|:.
Human    23 VFSGGQAVAG--RVLLELSSAARVGALRLRARGRAHVHWTESRSAGSSTAYTQSYSE----RVEV 81

  Fly    80 NGSKVHI-----NETKKL----NEVLQLENGTFRLGDFNFQLPENLPATCRLPFGNVEYVLKVVL 135
            ...:..:     .||..|    :|.|           |:||||..|..:.....|:|.|.:|..|
Human    82 VSHRATLLAPDTGETTTLPPGRHEFL-----------FSFQLPPTLVTSFEGKHGSVRYCIKATL 135

  Fly   136 ERRGTHNKCFQQRLVIRKCVEL---ADLKPQ-----------YMETANMGLT-----LPRSVFVP 181
            .|.....:..::...:.:.|::   |.|.||           |   .|.||.     :.|..:.|
Human   136 HRPWVPARRARKVFTVIEPVDINTPALLAPQAGAREKVARSWY---CNRGLVSLSAKIDRKGYTP 197

  Fly   182 GQSVS-YEICSKDGVQDFLTRLCKKISYTSQQPSAKTKNVTQVLSESSELNG----------NLR 235
            |:.:. :........:..|.|.....:.|.....|:.:....|.|.:.|..|          .||
Human   198 GEVIPVFAEIDNGSTRPVLPRAAVVQTQTFMARGARKQKRAVVASLAGEPVGPGQRALWQGRALR 262

  Fly   236 LPLTAPIMSHSDQLDPIQISYYIETFNSLNAP------IKVPIFVATV-APPVNSQTES 287
            :|...|.:.|...|   .:.|.::.  .::.|      :::|:.:.|: ..|..|::.|
Human   263 IPPVGPSILHCRVL---HVDYALKV--CVDIPGTSKLLLELPLVIGTIPLHPFGSRSSS 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18268	NP_649739.1	Arrestin_N	5..153	CDD:451447	28/146 (19%)
		Arrestin_C	172..279	CDD:460676	22/129 (17%)
ARRDC2	NP_056498.1	Arrestin_N	9..158	CDD:425619	29/151 (19%)
		Arrestin_C	181..307	CDD:214976	23/130 (18%)