Protein Alignment CG3014 and ROG3

DIOPT Version :10

• Sequence 1: NP_649738.1
• Gene: CG3014 / 40922
• FlyBaseID: FBgn0037519
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_116677.3
• Gene: ROG3 / 850578
• SGDID: S000001918
• Length: 733
• Species: Saccharomyces cerevisiae
• Alignment Length: 503
• Identity: 88/503 - (17%)
• Similarity: 176/503 - (34%)
• Gaps: 138/503 - (27%)

  Fly     8 QLDRLNPVY--------NSGEYISGRILLRTDKVKRVNAVYVTLEGEAKVQWSMSGKSETANYSG 64
            ::.:.|.|:        |..||:||                  |.|::    .::|.|.::|..|
Yeast    90 KIRKYNKVFYNYAWDNVNLKEYLSG------------------LRGQS----GLAGSSSSSNILG 132

  Fly    65 HQQYLHSRTNVF--------DNTLFRAGVHVYVLTLRIPPDCPSTCKG-PYGYIAYTISLTIDKP 120
            .:|...|.:::.        .:.....|.:.:..:..:|...|.:.:. |..::.|::...|::.
Yeast   133 TRQRAQSTSSLKSLKGSSSPSSCTLDKGNYDFPFSAILPGSLPESVESLPNCFVTYSMESVIERS 197

  Fly   121 WGF-DEVFRKPIIVVQTLDLNYNAEFSLPVKDENLKYLC---HWPCISGPICSTLTLPASGFTPL 181
            ..: |.:.||.|.|::|:.         |...|..:.:|   .||   ..:..::::|.......
Yeast   198 KNYSDLICRKNIRVLRTIS---------PAAVELSETVCVDNSWP---DKVDYSISVPNKAVAIG 250

  Fly   182 QEVPYRLEVDNQSPHYDIIGVEVSIKQHFVFLSRKP--VKRNFYSKTLVKELISDRTLRLSKRQY 244
            ...|..:.:...|....:..::|.:.:::.:....|  :..|    ..|.||..:..|..|..::
Yeast   251 SATPINISIVPLSKGLKLGSIKVVLFENYQYCDPFPPVISEN----RQVTELNLEDPLNESSGEF 311

  Fly   245 ESSICV---PMDTPRSTLNPNYIVFLHYTLQVKLKTGYFHYDTDLSVPIIVGTTSLQH------L 300
            ..:.|.   |...|            .::.|.|     :..||.|.:|     .||.:      :
Yeast   312 NGNGCFVNNPFFQP------------DHSFQDK-----WEIDTILQIP-----NSLSNCVQDCDV 354

  Fly   301 RDSVHTQQPVR---------------RTPTPERQRLIERVTPRPPTVEEDSAGEADPATDEPHRV 350
            |.::..:..::               |...|.:..:...|......:...:.......|::....
Yeast   355 RSNIKVRHKLKFFIILINPDGHKSELRASLPIQLFISPFVALSIKPLSSSNLYSLFSTTNQKDEN 419

  Fly   351 IEDDEPPSYDSCLPPSFSFATLAGSQQTLGSNAAVVLQRIHLPKFPGFSTLIGTAPAHGMEDSGL 415
            ...:|...|......|.:...|....::.||             .|..|.|: |.|.:
Yeast   420 SSQEEEEEYLFSRSASVTGLELLADMRSGGS-------------VPTISDLM-TPPNY------- 463

  Fly   416 DMHMY-RSY-GSLNTDHTGRSLDTFGSLCGPLSEH---VEEQEQEAEE 458
            :||:| |.| ||.    |..:::|.|: |.||...   ||:|:|:.|:
Yeast   464 EMHVYDRLYSGSF----TRTAVETSGT-CTPLGSECSTVEDQQQDLED 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3014	NP_649738.1	Arrestin_N	5..140	CDD:451447	27/149 (18%)
		Arrestin_C	164..294	CDD:214976	20/134 (15%)
ROG3	NP_116677.3	Arrestin_N	<156..215	CDD:451447	11/58 (19%)
		Arrestin_C	232..393	CDD:214976	27/189 (14%)