Protein Alignment CG10086 and RIM8

DIOPT Version :10

• Sequence 1: NP_649736.3
• Gene: CG10086 / 40920
• FlyBaseID: FBgn0037517
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_011470.4
• Gene: RIM8 / 852837
• SGDID: S000003013
• Length: 542
• Species: Saccharomyces cerevisiae
• Alignment Length: 578
• Identity: 104/578 - (17%)
• Similarity: 184/578 - (31%)
• Gaps: 195/578 - (33%)

  Fly     3 KNCMITFDQNEHGTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQWRIRRHGKAVAIQNPK 67
            |...|..|: .|..:...:.|||:.::::.:......|||.:....:.:.......|...|:...
Yeast    37 KQFRIDIDE-PHRVWKPNESITGEAVIDIKRDITNVAIKLSLVCEVRVKTGNSPTSKNKRIEKTL 100

  Fly    68 KRSKHQYSGREDYIAS-------------TTYLMGSEQG-----------------SNFNMDAGT 102
            ::|...|.  :||:.:             ||.|.|..:|                 |:...:.|:
Yeast   101 EKSTFLYG--QDYVKTAFSAKEKKPHVDKTTILNGLSKGEHRFPFRIRIPRGRGMLSSIKFERGS 163

  Fly   103 YTYTFACPIPSHCPSSFEGAYGHIRYLAKVTFL-KPGASNRTHNVGFTVLKLLDLNQ----ETK- 161
            .||..:|.:.|               |..:..| ||.|.....   |.|:..||:::    :||
Yeast   164 ITYFLSCTLES---------------LNNINGLKKPEARCERE---FAVIVPLDVSRLPKPKTKT 210

  Fly   162 MLREPAS------NEAVEHFCLMHT-------------------------KPVQLKVTLQQQGYV 195
            ::.:.||      |::.|.....:|                         |.|.:.|.:.|.|::
Yeast   211 VVLQSASMVQNKKNKSTEDESSSYTQLTQKSTTSNSSSSSVNSKTSPLPNKTVTISVDIPQAGFM 275

  Fly   196 PGQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSEKIMLV-------------KRE 247
            .|:  :|...|:.|            |.:..|.  ...|.||..:|..|             |..
Yeast   276 IGE--IIPIDVKID------------HYKPFYA--PAGLTTTLVRICRVGGAGKDDPMETFRKDI 324

  Fly   248 C---GPVAHNAQ------RTYTETLRIPATA-PTCEHLSKVVRVSYEVRVVAVM---NWLMANPR 299
            |   .|:..|.:      |.|   |::|..| .|...:.|.....|.:.|:..:   |.:.....
Yeast   325 CQSISPIYINPETLQFQSRVY---LKVPLDAFSTLTTVGKFFSFQYYIEVMVNLSKKNVVYTESN 386

  Fly   300 LIIPVTIGNVPLATAVSGPDFLPTNAFPSGSSLPADLPCTSTRAMELAQMAASGVSNSGYEMA-- 362
            .||...||.                  .:|..:..::.....:.:.:.........:.|||.:
Yeast   387 RIIGTPIGE------------------QNGLGVENNINRIQRKMLRMVNPETLENDSEGYESSIF 433

  Fly   363 -EDLEDFELPEDGDDELEAADDFVPDLPPPTYEQAMFMTTDIADT-------DANTVSEASRFTP 419
             :|:.:.|       :|:...:..          .|.:.|.|..|       ||:..|::|...|
Yeast   434 FKDMVNVE-------KLKRLRNVT----------GMSIETVIGTTRSEQQQSDASIPSQSSITAP 481

  Fly   420 R------------YPVFDVDTFQSPPPNPPQKKRRRRRRRPADPGQSKQQPEKQPVES 465
            :            ...:|.|....|..:|..|.     ..|::..|..:|...|.:||
Yeast   482 QNSPSNLRDWLAPLNAYDSDDVPVPKYSPNDKV-----SVPSEDKQELEQKRLQQLES 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:425619	35/182 (19%)
		Arrestin_C	180..311	CDD:214976	35/181 (19%)
RIM8	NP_011470.4	Arrestin_N	39..201	CDD:425619	35/182 (19%)
		Arrestin_C	259..392	CDD:460676	32/151 (21%)