DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10086 and ECM21

DIOPT Version :9

Sequence 1:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_009449.1	Gene:	ECM21 / 852173	SGDID:	S000000197	Length:	1117	Species:	Saccharomyces cerevisiae

Alignment Length:	365	Identity:	65/365 - (17%)
Similarity:	114/365 - (31%)	Gaps:	152/365 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 NPKKR----------SKHQYSGREDYIASTTYLMGSEQGSNFNMDAGTYTYTFACPIPSHC---- 115
            |||:|          :|.::...||....|..::     ..:.:||    || :.|.|.|.
Yeast   714 NPKERLGITEPIIIETKLKFPKYEDLDKRTAKII-----PPYGIDA----YT-SIPNPEHAVANG 768

  Fly   116 PSSFEGAYGHIRYLAKVTFLKPGASNRTHNVGFTVLKLLDLNQETKMLREPASNEAVEHFCLMHT 180
            ||.        |..:.:.||.....:::|            .:..|.:.:|..::.:
Yeast   769 PSH--------RRPSVIGFLSGHKGSKSH------------EENEKPVYDPKFHQTI-------- 805

  Fly   181 KPVQLKVTLQQQGYVPGQFMLIHAHVR-------------NDSSSDCR-KLLIMLHL-------- 223
                    ::....:|     :..|.|             :.|:..|| ||.|||.:
Yeast   806 --------IKSNSGLP-----VKTHTRLNTPKRGLYLDSLHFSNVYCRHKLEIMLRISKPDPECP 857

  Fly   224 ----RATYTADTPSLRTTSEKIMLVKRECG---------------------PVAHNAQ------- 256
                ......|||        |.||..:|.                     |::.|:.
Yeast   858 SKLRHYEVLIDTP--------IFLVSEQCNSGNMELPTYDMATMEGKGNQVPLSMNSDFFGNTCP 914

  Fly   257 --RTYTETLRIPATAPTCEHLSKVVRVSYEVRVVAVMNWLMANPRLIIPVTIGNVPLATAVSGPD 319
              .|:.|.:.:||:.......|..:..||:..::::...              |:...|:|||
Yeast   915 PPPTFEEAISVPASPIVSPMGSPNIMASYDPDLLSIQQL--------------NLSRTTSVSG-- 963

  Fly   320 FLPTNAFPSGSSLPADLPCTSTRAMELAQMAASGVSNSGY 359
                   |||.|..|.:|..:..::..|......:|||.:
Yeast   964 -------PSGYSDDAGVPNVNRNSISNANAMNGSISNSAF 996

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	21/105 (20%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	27/184 (15%)
ECM21	NP_009449.1	Arrestin_C	585..>648	CDD:214976
ECM21	NP_009449.1	Arrestin_C	<781..878	CDD:413500	20/137 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343367
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930