Protein Alignment CG10086 and ROG3

DIOPT Version :10

• Sequence 1: NP_649736.3
• Gene: CG10086 / 40920
• FlyBaseID: FBgn0037517
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_116677.3
• Gene: ROG3 / 850578
• SGDID: S000001918
• Length: 733
• Species: Saccharomyces cerevisiae
• Alignment Length: 484
• Identity: 82/484 - (16%)
• Similarity: 161/484 - (33%)
• Gaps: 163/484 - (33%)

  Fly    22 VITGKVIVNLNKTKKLRGIKLQISGYAQAQWRIRR----HGKAVAIQNPKKRS------------ 70
            :::|.:::::|:..:::.|.|::.|..|....:.|    ...:::...||.|.
Yeast    41 LLSGCIVLSINEPMQIKSISLRLYGKIQIDVPLERPQDASSSSLSSSPPKIRKYNKVFYNYAWDN 105

  Fly    71 ---KHQYSG---------------------REDYIASTTYLMGSEQGSNFNMDAGTYTYTFACPI 111
               |...||                     |....:|...|.||...|:..:|.|.|.:.|:..:
Yeast   106 VNLKEYLSGLRGQSGLAGSSSSSNILGTRQRAQSTSSLKSLKGSSSPSSCTLDKGNYDFPFSAIL 170

  Fly   112 PSHCPSSFEGAYGHIRYLAKVTFLKPGASNRTHNVGFTVLKLLDLNQETKMLR--EPASNEAVEH 174
            |...|.|.|....     ..||:.......|:.|....:.:     :..::||  .||:.|..|.
Yeast   171 PGSLPESVESLPN-----CFVTYSMESVIERSKNYSDLICR-----KNIRVLRTISPAAVELSET 225

  Fly   175 FCLMHTKPVQLKVTLQQQGYVPGQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSE 239
            .|:.::.|.::..::.    ||.:.:.|      .|::.....::.|         :..|:..|.
Yeast   226 VCVDNSWPDKVDYSIS----VPNKAVAI------GSATPINISIVPL---------SKGLKLGSI 271

  Fly   240 KIMLVK--RECGP----VAHNAQRT--------------------------------------YT 260
            |::|.:  :.|.|    ::.|.|.|                                      ..
Yeast   272 KVVLFENYQYCDPFPPVISENRQVTELNLEDPLNESSGEFNGNGCFVNNPFFQPDHSFQDKWEID 336

  Fly   261 ETLRIPATAPTCEHLSKV---VRVSYEVRVVAVMNWLMANP-------RLIIPVTIGNVPLATAV 315
            ..|:||.:...|.....|   ::|.::::...:    :.||       |..:|:.:...|
Yeast   337 TILQIPNSLSNCVQDCDVRSNIKVRHKLKFFII----LINPDGHKSELRASLPIQLFISP----- 392

  Fly   316 SGPDFLPTNAFPSGSSLPADLPCT-------STRAMELAQMAASGVSNSGYEMAEDLEDFELPED 373
                |:..:..|..||....|..|       |::..|...:.:...|.:|.|:..|:.
Yeast   393 ----FVALSIKPLSSSNLYSLFSTTNQKDENSSQEEEEEYLFSRSASVTGLELLADMR------- 446

  Fly   374 GDDELEAADDFVPD----LPPPTYEQAMF 398
                   :...||.    :.||.||..::
Yeast   447 -------SGGSVPTISDLMTPPNYEMHVY 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:425619	31/174 (18%)
		Arrestin_C	180..311	CDD:214976	25/184 (14%)
ROG3	NP_116677.3	Arrestin_N	<156..215	CDD:451447	14/68 (21%)
		Arrestin_C	232..393	CDD:214976	26/192 (14%)