DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10086 and si:ch211-130m23.2

DIOPT Version :9

Sequence 1:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001108161.1	Gene:	si:ch211-130m23.2 / 794173	ZFINID:	ZDB-GENE-060531-13	Length:	441	Species:	Danio rerio

Alignment Length:	471	Identity:	99/471 - (21%)
Similarity:	183/471 - (38%)	Gaps:	98/471 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KNCMITFDQ-NEHGTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQWRIRRHGKAVAIQNP 66
            ||..:.::. |::.|:.:|..|:|:||:::.|..:::.:.::|.|.|...|. ..:||.....:.
Zfish     6 KNISVIYNPINQNNTFTSGDYISGQVILDVVKDTQMQSLSVKIKGKANVCWS-EHYGKTTVCYSD 69

  Fly    67 KKRSKHQYSGREDYIASTTYLMGSEQGSNFNM---DAG------------TYTYTFACPIPSHCP 116
            |::.   ||....::.:.|     :||::..|   .:|            .|.:||..|: .|.|
Zfish    70 KEKF---YSVERFFVRTDT-----KQGTDHEMLKDPSGQPYSSVVAPGRHLYPFTFQLPL-QHFP 125

  Fly   117 SSFEGAYGHIRYLAKVTFLKPGASNRTHNVGFTVLKLLDL-NQETKMLREPASNEAVEHFCLMHT 180
            ||.:|:.|.:.|..:....:....:......|..:...|: |.|   |..|......:.....::
Zfish   126 SSLKGSVGKVLYTLETKLCRSLRVSSKAKAEFNYVPSADISNPE---LMAPQYGTIDKQMKFFNS 187

  Fly   181 KPVQLKVTLQQQGYVPGQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSEKIMLVK 245
            ..|.:.::.::..|..|:.:.:.|.:.|.||...:....:....:.:......:.|..    |:|
Zfish   188 GNVSMNISTEKMAYYLGEGLKVLAEIHNGSSRIIKPKYCLYEKYSFFAKGRRKIHTHD----LLK 248

  Fly   246 RECGPVAHNAQRTYTETLRIPATAPTCEHLSKVVRVSYEVRVVAVMNWLMANPRLIIPVTIGNVP 310
            .....|..|:::|.|..|.||.:........::::|.|.:||...:.: .::|.:.:|:.:  :|
Zfish   249 EVGESVEPNSKKTITTVLTIPPSLTASILNCRILKVEYRLRVYLDVKY-ASDPEIKLPIVV--LP 310

  Fly   311 LATAVSGPDFLPTNAFPSGSSLPADLPCTSTRAMELAQMAASGVSNSGYEMAEDLEDFELPEDGD 375
            | ..|||                                 |:|.:.|      |...:..|:.|.
Zfish   311 L-QPVSG---------------------------------ANGSTKS------DFGIWNQPQPGS 335

  Fly   376 DELEAADDFVPDLPPPTYEQAMFMTTDIADTDANTVSEASRFTPRYPVFDVDTFQSPP--PNPPQ 438
            ..        |: ||||...|  .:.:||.......:      |.||...|..| |||  |.||
Zfish   336 AG--------PN-PPPTAPSA--QSQNIAGPPGQLGA------PDYPGPPVGQF-SPPSYPGPP- 381

  Fly   439 KKRRRRRRRPADPGQS 454
            ..:......|..||||
Zfish   382 LDQFGALAFPGPPGQS 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	35/168 (21%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	23/128 (18%)
si:ch211-130m23.2	NP_001108161.1	Arrestin_N	16..166	CDD:304627	35/159 (22%)
		Arrestin_C	187..309	CDD:280848	23/128 (18%)
		Collagen	333..408	CDD:189968	25/84 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579457
Domainoid	1	1.000	65	1.000	Domainoid score	I10015
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		otm24709
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.750