DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10086 and Arrdc2

DIOPT Version :9

Sequence 1:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_081836.1	Gene:	Arrdc2 / 70807	MGIID:	1918057	Length:	407	Species:	Mus musculus

Alignment Length:	463	Identity:	111/463 - (23%)
Similarity:	176/463 - (38%)	Gaps:	111/463 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KNCMITFDQNEHGT---YFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQW-RIRRHGKAVAI 63
            |..::..|....||   :..||.:.|:|::.|....::..::|:..|.|:|.| ..|..|.:.|.
Mouse     7 KAFVVEIDGARTGTEPVFHGGQAVAGRVLLELAGAARVGALRLRARGRARAHWTESRSAGSSTAY 71

  Fly    64 QNPKKRSKHQYSGREDYIASTTYLMGSEQGSNFNMDAGTYTYTFACPIPSHCPSSFEGAYGHIRY 128
                   ...||.|.:.:.....|:..:.|....:.||.:.:.|:..:|....:||||.:|.:||
Mouse    72 -------TQSYSERVEVVNHRATLLAPDSGDIATLPAGRHEFPFSFQLPISLVTSFEGKHGSVRY 129

  Fly   129 LAKVTFLKPGASNRTHNVGFTVLKLLDLNQETKMLREP--ASNEAVEHFCLMHTKPVQLKVTLQQ 191
            ..|.|..:|....|.....|||::.:|:|  |..|.||  .:.|.|..........|.|...:.:
Mouse   130 SIKATLHRPWVPARCARKVFTVIEPVDIN--TPALLEPQAGAREKVARSWYCTRGLVSLSAKIDR 192

  Fly   192 QGYVPGQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSEKIMLVKRECGPVAHNAQ 256
            :||.||:.:.|.|.:.|.|:   |.:.....|..|.|......| ..::.::...:..||..|.:
Mouse   193 KGYTPGEVIPIFAEIDNGST---RAVQPRAALVQTQTFMARGAR-KQKRAVVASVDGEPVGPNRR 253

  Fly   257 RTYT-ETLRIPATAPT---CEHLSKVVRVSYEVRVVAVMNWLMANPRLI--IPVTIGNVP----- 310
            ..:. ..||||...|:   |    :|:.|.|.::|...   :..:.:|:  :|:.||.||
Mouse   254 ALWPGRALRIPPVGPSILQC----RVLSVDYSLKVFVD---IPGSSKLLLELPLVIGTVPLHPLG 311

  Fly   311 -----------------LATAVSGPDFLP-----------TNAFPSGSSLPADLPCTSTRAMELA 347
                             |.|.:..|:..|           ..|.|..|||..||
Mouse   312 SRSASVGSRASFLQDWGLCTMMDRPEAPPEYSEVVRESQLVCASPGPSSLLHDL----------- 365

  Fly   348 QMAASGVSNSGYEMAEDLEDFELPEDGDDELEAADDFVPDLPPPTYEQAMFMTTDIADTDANTVS 412
                 ||:..|...| .|::|..                 .|||.|          ::.|.|..|
Mouse   366 -----GVTTEGPYFA-CLQEFRY-----------------CPPPLY----------SEEDPNPPS 397

  Fly   413 EASRFTPR 420
            ||.|  ||
Mouse   398 EAVR--PR 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	40/155 (26%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	31/134 (23%)
Arrdc2	NP_081836.1	Arrestin_N	9..158	CDD:278754	40/155 (26%)
Arrdc2	NP_081836.1	Arrestin_C	180..307	CDD:214976	33/137 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7292
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		otm42766
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.820