DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10086 and arrdc3

DIOPT Version :9

Sequence 1:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001016843.1	Gene:	arrdc3 / 549597	XenbaseID:	XB-GENE-5732341	Length:	412	Species:	Xenopus tropicalis

Alignment Length:	420	Identity:	105/420 - (25%)
Similarity:	179/420 - (42%)	Gaps:	59/420 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KNCMITFD--QNEH-GTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQW-RIRRHGKAVA- 62
            |:..|:||  ...| ..|.:|..::|:|.:.:....:::.:::...|:|:.:| ..|..|...|
Frog     7 KSLTISFDCLNGSHVPVYSSGDAVSGRVNLEVTGEIRVKSLRIHARGHAKVRWTESRNAGSNTAY 71

  Fly    63 IQNPKKRSKHQYSGREDYIASTTYLMG-------SEQGSNFNMDAGTYTYTFACPIPS-HCPSSF 119
            .||        |:...:|.:....|:|       ||:|.. .:.:|.:.|.|:..:|. ...:||
Frog    72 TQN--------YTEEVEYFSHKDILIGHERDDDNSEEGLT-TIHSGRHEYAFSFELPQIPLATSF 127

  Fly   120 EGAYGHIRYLAKVTFLKPGASNRTHNVGFTVLKLLDLNQETKMLREPASNEAVEHFC--LMHTKP 182
            ||.:|.:||..|....:|..........|||.:.:|:|  |..|..|.:....:..|  |..:.|
Frog   128 EGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDIN--TPSLLAPQAGTKEKTLCCWLCTSGP 190

  Fly   183 VQLKVTLQQQGYVPGQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSEKI-MLVKR 246
            :.|...::::||.||:.:.|.|.:.|.||.      :::...|.|...|...:...::: .||..
Frog   191 ISLSAKIERKGYTPGESIQIFAEIENCSSR------MVVPKAALYQTQTFYAKGKMKEVKQLVAN 249

  Fly   247 ECGPVAHNAQRTYTET-----LRIPATAPTCEHLSKVVRVSYEVRVVAVMNWLMANPRLIIPVTI 306
            ..|....:.:   |||     |:||..:|:....| ::||.|.:.|...:...| :..|.:|:.|
Frog   250 LRGESLSSGK---TETWNGKLLKIPPISPSIIDCS-IIRVEYSLMVYVDIPGAM-DLFLNLPLVI 309

  Fly   307 GNVPLATAVSGPDFLPTNAFPSGSSLPADLPCTSTRAMELAQMAASGVSNSGYEMAEDL------ 365
            |.:||     .|....|::..|..|:...|..|.....|.....|..|:.   |..::|
Frog   310 GTIPL-----HPFGSRTSSVSSQYSINNWLGLTLPERPEAPPSYAEVVTE---EQRQNLMSSNAC 366

  Fly   366 EDFELPEDGDDELEAADDFVPDLPPPTYEQ 395
            ::|||...|  .|.|.......||||.|.:
Frog   367 DNFELALQG--PLFAYIQEFRFLPPPLYSE 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	40/164 (24%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	33/134 (25%)
arrdc3	NP_001016843.1	Arrestin_N	9..165	CDD:334019	40/164 (24%)
arrdc3	NP_001016843.1	Arrestin_C	187..314	CDD:214976	34/137 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	85	1.000	Domainoid score	I8042
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		mtm9421
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920