Protein Alignment CG10086 and Leash

DIOPT Version :10

• Sequence 1: NP_649736.3
• Gene: CG10086 / 40920
• FlyBaseID: FBgn0037517
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 480
• Identity: 122/480 - (25%)
• Similarity: 198/480 - (41%)
• Gaps: 78/480 - (16%)

  Fly     2 SKNCMITFDQNEHGTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQWR--IRRHGKAVAIQ 64
            |:...||.|..:. .||.|.:|.|::.:|:||..|:|.||:|::|..:.:|.  :|::..    .
  Fly     3 SERLRITLDSADR-VYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSN----N 62

  Fly    65 NPKKRSKHQYSGREDYIASTTYLMGSEQGSNFNMDAGTYTYTFACPIPSHCPSSFEGAYGHIRYL 129
            |...||.. |:.:|.|..|.|.|...|. ....:.||.:|:.|...:....||||:|:||.|:|.
  Fly    63 NEYSRSLF-YTSKEVYEHSETPLPDFEP-RGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKYK 125

  Fly   130 AKVTFLKPGASNRTHNVGFTVLKLLDLNQETKMLREPASNEAVEHFCLMHTKPVQLKVTLQQQGY 194
            .:|...:|...:..|.:.|||:|.:.|....:.:......:..:...|..|:|:.|...|.:...
  Fly   126 MRVLIQRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFA 190

  Fly   195 VPGQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSEKIMLVKRECGPVAHNAQRTY 259
            |.|:.:.|.|.|.|:|::...||...:....||.:..|......|.|.:..:|.|.|....:|::
  Fly   191 VRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAVATKETGSVQKKTERSF 255

  Fly   260 TETLRIPATA-PTCEHLSKVVRVSYEVRVVAVMNWLMANPRLIIPVTIGNVPLATAVS------- 316
            ...|.:|..| ||.|.:|.|:.:.||:||.||:.....|..|.:|..:.:...:...|
  Fly   256 AHELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFKNLILNLPFKVYSQDPSNRQSSLRPPPP 320

  Fly   317 --------GPDFLPTNAF----------------PSGSSLPADLPCTSTRAMELAQMAAS----- 352
                    ||:....|.|                ||.||..::  |:|..::.....||:
  Fly   321 PRPNDGPPGPELGSGNLFEPALPVYPSLDSSIGSPSHSSQFSE--CSSINSITSDSSAATLSPAV 383

  Fly   353 GVSNSGYEMA----EDLEDFELPEDGDDELEAADDFVPDLPPPTYEQAMFMTTDIADTDANTVSE 413
            |....|.:|:    .....:..| .....|.:::  ||.:|   |..:..|.
  Fly   384 GAGTGGMDMSYTSGSQSSQYGSP-SARTSLRSSN--VPYMP---YSSSPLMV------------- 429

  Fly   414 ASRFTPRYPVFDVDTFQSPPPNPPQ 438
            .|...|..|.:       |||..||
  Fly   430 QSYPPPHLPAY-------PPPESPQ 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:425619	49/153 (32%)
		Arrestin_C	180..311	CDD:214976	39/131 (30%)
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	49/152 (32%)
		Arrestin_C	191..308	CDD:214976	35/116 (30%)