DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10086 and CG2641

DIOPT Version :9

Sequence 1:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_649737.1	Gene:	CG2641 / 40921	FlyBaseID:	FBgn0037518	Length:	429	Species:	Drosophila melanogaster

Alignment Length:	453	Identity:	112/453 - (24%)
Similarity:	177/453 - (39%)	Gaps:	77/453 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKNCMITFDQNEHGTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQW---RIRRHGKAVA 62
            |..:|....|:.| ..|::|:.:.|:.|:.....|.:..:.:...|.|:.:|   |.|..|
  Fly     1 MPSSCSFELDRRE-PIYYSGETVNGRAILTTTSEKSVNEVYILFEGEAKVRWDERRTRTRG---- 60

  Fly    63 IQNPKKRSKH---QYSGREDYIASTTYLMGSEQGSNFNMDAGTYTYTFACPIPSHCPSSFEGAYG 124
                 .:::|   .:.|::.|:.:.|.:.||.     |:..||:||.|..|:|..||||....||
  Fly    61 -----GKTEHYTEYFRGKQQYLYTRTSVFGSG-----NLPPGTHTYNFCIPLPLECPSSVVAQYG 115

  Fly   125 HIRYLAKVTFLKPGASNRTHNVGFTVLKLLDLNQETKMLREPASNEAVEHFCL--MHTKPVQLKV 187
            .|.|...|...:....|.......||::..:||...::|. |...|.::|||.  ..:.||...:
  Fly   116 KIFYEVSVVIDRQWRFNNVFKQPLTVIQTYNLNMSPQLLM-PLVREDIKHFCCWPCSSGPVLSTL 179

  Fly   188 TLQQQGYVPGQFMLIHAHVRNDSSS-DCRKLLIMLHLRATYTADTPSLRTTSEKIMLVKRECGP- 250
            |:...||.|||.:.....:.|.||. |...:.:.|.....:.|.||. ..|.||...:.:.|..
  Fly   180 TIPFGGYAPGQKIRFTLEIDNQSSGYDLNGIELKLKQIYKFQAQTPH-HKTREKEHSLNKSCQQE 243

  Fly   251 -VAHNAQRTYTETLRIPATAPTCEHLSKVVRVSYEVRVVAVMNWLMANPRLIIPVTIGNVPLATA 314
             |...:::....||.|||..|: .....::.|||:|.:.........:....:|:.||.:||..:
  Fly   244 RVLRLSKKKIEGTLAIPAVPPS-SRTEGIISVSYQVILTISTGDCHVDSDFEVPIVIGTIPLIQS 307

  Fly   315 VSGPDFLPTNAFPSGSSLPADLPCTSTRAMELAQMAASGVSNSGYEMAEDLEDFELPEDGDDELE 379
            ...|                         ...||.                    :||..|....
  Fly   308 AENP-------------------------ASAAQW--------------------IPETPDTPAG 327

  Fly   380 AADDFVPD---LPPPTYEQAMFMTTDIADTDANTVSEASRFTPRYPVFDVDTFQSPPPNPPQK 439
            ||.|..|.   ..|||:|:|........|.|.:..:....|.||||::......|.||.||::
  Fly   328 AAADLPPSYDKCKPPTFEEATNFGERFIDIDQDEHNRTDDFIPRYPMYTNFAMPSAPPQPPEE 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	40/157 (25%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	33/131 (25%)
CG2641	NP_649737.1	Arrestin_N	5..148	CDD:278754	40/157 (25%)
CG2641	NP_649737.1	Arrestin_C	171..301	CDD:280848	33/131 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464077
Domainoid	1	1.000	63	1.000	Domainoid score	I10233
eggNOG	1	0.900	-	-		E1_KOG3780
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	43	1.000	Inparanoid score	I2088
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110793at6960
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		otm24709
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
	10	9.900