Protein Alignment CG10086 and ARRB2

DIOPT Version :9

• Sequence 1: NP_649736.3
• Gene: CG10086 / 40920
• FlyBaseID: FBgn0037517
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: XP_011522160.1
• Gene: ARRB2 / 409
• HGNCID: 712
• Length: 440
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 90/472 - (19%)
• Similarity: 156/472 - (33%)
• Gaps: 179/472 - (37%)

  Fly    46 GYAQAQWRIRRHGK--------AVAIQNP-----KKRSKH----QYSGREDYI------------ 81
            |..::|.|.:|.|.        ..||:..     ||.|.:    .|.|:.|::
Human     8 GLGRSQTRAQRRGSGGRTPGSLGTAIRGRTRRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGV 72

  Fly    82 ----------------ASTTYLMGSEQ----GSNFNMDAGTYTYTFACPIPS--HCPSSFE---- 120
                            .:..:..|.|.    |.:|..|....||....|:|:  ..|:..:
Human    73 VLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLL 137

  Fly   121 ---GAYGHIRYL-------AKVTFLKPGA--SNRTHNVGFTVLKLLDLNQETK---------MLR 164
               |.:.|..:.       ..|| |:||.  :.:...|.|.:......:.|.|         ::|
Human   138 RKLGQHAHPFFFTIPQNLPCSVT-LQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIR 201

  Fly   165 E----------PASNEAVEHFCLMHTKPVQLKVTLQQQGYVPGQFMLIHAHVRNDSSSDCRKLLI 219
            :          ..|.|...|| ||..:.:.|:.:|.::.|..|:.:.::.||.|:|:...:|:.:
Human   202 KVQFAPEKPGPQPSAETTRHF-LMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKV 265

  Fly   220 MLHLRA-------------------------------TYTADTPSLRTTSEKIMLVKRECGPVAH 253
            .:...|                               .||. ||.|....||..|...  |.:.|
Human   266 SVRQYADICLFSTAQYKCPVAQLEQDDQVSPSSTFCKVYTI-TPLLSDNREKRGLALD--GKLKH 327

  Fly   254 NAQRTYTETLRIPATAPTCEHLSKVV---RVSYEVRVVAVMN----------WLMANPRLIIPVT 305
                   |...:.::....|..:|.|   .|||.|:|..|::          :::.:|:     .
Human   328 -------EDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPK-----P 380

  Fly   306 IGNVPLATAVSGPDFLPTNAFPSGSSLPADLPCTSTRAMELAQMAASGVSNSGYEMAEDL--EDF 368
            ..::||..        |.:|.|. :.:|.|     |..:|.         ::.|...:|:  |||
Human   381 HDHIPLPR--------PQSAAPE-TDVPVD-----TNLIEF---------DTNYATDDDIVFEDF 422

  Fly   369 E-------LPEDGDDEL 378
            .       ..:|.||:|
Human   423 ARLRLKGMKDDDYDDQL 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	32/177 (18%)
		Arrestin_C	179..308	CDD:280848	31/172 (18%)
ARRB2	XP_011522160.1	Arrestin_N	50..206	CDD:278754	25/156 (16%)
		Arrestin_C	225..380	CDD:214976	31/169 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910