DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10086 and AgaP_AGAP001821

DIOPT Version :9

Sequence 1:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	XP_550973.4	Gene:	AgaP_AGAP001821 / 3290520	VectorBaseID:	AGAP001821	Length:	355	Species:	Anopheles gambiae

Alignment Length:	411	Identity:	118/411 - (28%)
Similarity:	172/411 - (41%)	Gaps:	89/411 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CMITFDQNEHGTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQWRIRRHGKAVAIQNPK-K 68
            |.|.||.|..|.:..|..:||.:.::|.|.||:||:.|.||||:...|      :|.....|| |
Mosquito    12 CDILFDDNSSGIFTAGDRVTGVIELHLTKIKKVRGVCLLISGYSAVLW------EAKVPDGPKNK 70

  Fly    69 RSKHQYSGREDYIASTTYLMGSEQGSNFNMDAGTYTYTFACPIPSHCPSSFEGAYGHIRYLAKVT 133
            :.|.|:.||||:|....||.|||.|:...:......|.|...||...|:|.||.|||:|||.:||
Mosquito    71 KVKAQFKGREDFIKQKQYLAGSENGAGMQLPPNLVRYKFDFSIPPEAPTSMEGKYGHVRYLLQVT 135

  Fly   134 FLKPGASNRTHNVGFTVLKLLDLNQETKMLREPASNE-AVEHFC-LMHTKPVQLKVTLQQQGYVP 196
            ..:|...:......|||:...||||..::|..|...| .:..:| |..::|:.:..|..:.||.|
Mosquito   136 LERPWKFDHNFQQPFTVVCRADLNQSNEVLCIPTRAENMMTFYCGLCRSRPLMVSATTPKSGYAP 200

  Fly   197 GQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSEKIMLVKRECGPVAHNAQRTYTE 261
            |:.:.:...|:|.|......:.|.......:|:.|..:..|    .:.|.|     .|.|....|
Mosquito   201 GETIELEVFVQNSSKVTVSVIEIRWQKILKFTSQTRVIGQT----QIPKEE-----SNVQYEVLE 256

  Fly   262 TLRIPA----------------TAPTCE--HLSKVVRVSYEVRVVAVMNWLMANPRLIIPVTIGN 308
            ..:||:                ..|:.|  | |::|.|.||:.:|..........:|.||:|||.
Mosquito   257 VRKIPSIEGENDARFVESFVVGPVPSTETTH-SRIVAVEYELALVVKPQASTKRMKLNIPITIGQ 320

  Fly   309 VPLATAVSGPDFLPTNAFPSGSSLPADLPCTSTRAMELAQMAASGVSNSGYEMAEDLEDFELPED 373
            :|||                ||::|                         |.|:..|:..   .|
Mosquito   321 IPLA----------------GSAMP-------------------------YAMSGGLQKL---ND 341

  Fly   374 GDDELEAADDFVPDLPPPTYE 394
            ..:|..:|        ||.||
Mosquito   342 TLNEHSSA--------PPAYE 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	59/152 (39%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	34/146 (23%)
AgaP_AGAP001821	XP_550973.4	Arrestin_N	12..159	CDD:304627	59/152 (39%)
AgaP_AGAP001821	XP_550973.4	Arrestin_C	183..323	CDD:214976	35/149 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H119234
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46400
OrthoDB	1	1.010	-	-		D110793at6960
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X122
TreeFam	0	0.000	Not matched by this tool.
	8	7.930