Protein Alignment CG10086 and Arrdc3

DIOPT Version :10

• Sequence 1: NP_649736.3
• Gene: CG10086 / 40920
• FlyBaseID: FBgn0037517
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001007798.1
• Gene: Arrdc3 / 309945
• RGDID: 1359478
• Length: 414
• Species: Rattus norvegicus
• Alignment Length: 487
• Identity: 107/487 - (21%)
• Similarity: 190/487 - (39%)
• Gaps: 115/487 - (23%)

  Fly     3 KNCMITFD---QNEHGTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQW-RIRRHGKAVA- 62
            |:..|:||   .:....|.:|..::|:|.:.:....:::.:|:...|:|:.:| ..|..|...|
  Rat     7 KSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAGSNTAY 71

  Fly    63 IQNPKKRSKHQYSGREDYIASTTYLMGSEQGSN------FNMDAGTYTYTFACPIP-SHCPSSFE 120
            .||        |:...:|......|:|.|:..:      ..:.:|.:.|.|:..:| :...:|||
  Rat    72 TQN--------YTEEVEYFNHKDILIGHERDDDNCEEGFSTIHSGRHEYAFSFELPQTPLATSFE 128

  Fly   121 GAYGHIRYLAKVTFLKPGASNRTHNVGFTVLKLLDLNQETKMLREPASNEAVEHFC--LMHTKPV 183
            |.:|.:||..|....:|..........|||.:.:|:|  |..|..|.:....:..|  ...:.|:
  Rat   129 GRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDIN--TPSLLSPQAGTKEKTLCCWFCTSGPI 191

  Fly   184 QLKVTLQQQGYVPGQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSEKIMLVKREC 248
            .|...::::||.||:.:.|.|.:.|.||........:...:|.|...  .::...:.:..::.|
  Rat   192 SLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKG--KMKEVKQLVANLRGE- 253

  Fly   249 GPVAHNAQRTYT---ETLRIPATAPTCEHLSKVVRVSYE----VRVVAVMNWLMANPRLIIPVTI 306
               :.::.:|.|   :.|:||..:|:....| ::||.|.    |.:...|:.|::     :|:.|
  Rat   254 ---SLSSGKTETWDGKLLKIPPVSPSILDCS-IIRVEYSLMVYVDIPGAMDLLLS-----LPLVI 309

  Fly   307 GNVPL------ATAVSGPDFLPTNAFPSGSSLP---------ADLPCTSTRAMELAQMAASGVSN 356
            |.:||      .::||....:..|..  |.|||         |::.....|...||.::|
  Rat   310 GTIPLHPFGSRTSSVSSQCSMNMNWL--GLSLPERPEAPPSYAEVVTEEQRRNNLAPVSA----- 367

  Fly   357 SGYEMAEDLEDFELPEDGDDELEAADDFVPDLPPPTYEQAMFMTTDIADTDANTVSEASRFTPRY 421
                    .:|||....|  .|.|.......||||.|.
  Rat   368 --------CDDFERALQG--PLFAYIQEFRFLPPPLYS--------------------------- 395

  Fly   422 PVFDVDTFQSPPPNPPQKKRRRRRRRPADPGQ 453
               ::|      |||.|..    ..||:.|.:
  Rat   396 ---EID------PNPDQSS----EDRPSCPSR 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:425619	38/163 (23%)
		Arrestin_C	180..311	CDD:214976	30/137 (22%)
Arrdc3	NP_001007798.1	Arrestin_N	22..165	CDD:425619	35/150 (23%)
		Arrestin_C	187..314	CDD:214976	30/138 (22%)
		PPxY motif 1. /evidence=ECO:0000305	346..349		0/2 (0%)
		PPxY motif 2. /evidence=ECO:0000305	391..394		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	393..414		9/60 (15%)