DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10086 and SPAC31A2.12

DIOPT Version :9

Sequence 1:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_592924.1	Gene:	SPAC31A2.12 / 2542940	PomBaseID:	SPAC31A2.12	Length:	596	Species:	Schizosaccharomyces pombe

Alignment Length:	481	Identity:	80/481 - (16%)
Similarity:	169/481 - (35%)	Gaps:	130/481 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 ITGKVIVNLNKTKKLRGIKLQISGYAQAQWRIRRHGKAVAIQNPKKRSKHQYSGREDYIASTTYL 87
            ::|.|::.||:...::.|.|::.|..:..|         :..:|..|...:::.:|..:....::
pombe    39 LSGSVVLCLNEAISVKAISLKLVGKCRISW---------SEPSPTVRGGQRHNKQEYVVYEKNWI 94

  Fly    88 MGSEQGSNFNMDAGTYTYTFACPIPSHCPSSFEGAYG-HIRYLAKVTFLKPGASNRTHNVGFTVL 151
            .....|:|..:.||.|.|.|...:|.....|.||... ::.|..|.:..:.|.:::       ::
pombe    95 FVPYTGANRTLRAGNYEYPFHVMLPGDIAESVEGLQSCYVVYRLKASIDRTGLASK-------MV 152

  Fly   152 KLLDLNQETKMLRE-PASNEAVEH---FCLMHTKP--VQLKVTLQQQGYVPGQFMLIH------- 203
            |    .:..:::|. ||  :|:|:   ..:.:|.|  ::..:::..:.|..|.::.||
pombe   153 K----KKHIRLIRALPA--DAIEYTQTISVDNTWPNKIEYTISVPTKAYAIGSYIPIHFVLVPLL 211

  Fly   204 AHVRNDSSSDCRKLLIMLHLRATYT---ADTPSLRTTSEKIMLVKRECGPVAHNAQRTYTETLRI 265
            ..:.....|...|..|.||:...|.   |....:||...   |...|....:.:.:  .|:.|.:
pombe   212 KRLTIGKISITLKEYITLHVAHGYNGLPASKDEVRTVRS---LQTEELEEFSDHYE--LTKNLEL 271

  Fly   266 PATAPTCEHLSKVVRVSYEVRVVAVMNWLMANP-------RLIIPVTIGNVPLATAVSGPDFLPT 323
            |::...|  |........::|.....:..:.||       |..:||.:             .:|.
pombe   272 PSSLVEC--LQDCDLDGIKIRHKLKFSVSLRNPDGHISELRAALPVVL-------------MIPP 321

  Fly   324 NAFPSGSSLPADLPCTSTRAMELAQMAASGVSNSGYEMAEDLEDFELPEDGDDELEAADDFVPDL 388
            ..|...:.:.:                          :.|:.|.|                  :.
pombe   322 QLFGDRAEVES--------------------------LRENFESF------------------NQ 342

  Fly   389 PPPTYEQAMF--MTTDIADTDANTVSEASRFTPRYPVFDVDTFQSPPPNPPQKKRRRR------- 444
            |.|:|:.:|:  :...::.::.:|...:...|||       ...|..|.....:..||
pombe   343 PLPSYQNSMYDRLYDGLSYSNLDTPLPSGATTPR-------RRDSMEPTYASNEAHRRQLIAGLT 400

  Fly   445 ----RRRPADPGQSKQQPEKQPVESP 466
                :::|.....::..|...|.:.|
pombe   401 ELALQQQPQGRSPNEHSPSNHPEDFP 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	26/134 (19%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	28/147 (19%)
SPAC31A2.12	NP_592924.1	Arrestin_N	38..144	CDD:304627	24/113 (21%)
SPAC31A2.12	NP_592924.1	Arrestin_C	180..321	CDD:214976	27/160 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	52	1.000	Domainoid score	I3293
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910