DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10086 and SPCC584.15c

DIOPT Version :9

Sequence 1:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_588220.1	Gene:	SPCC584.15c / 2539284	PomBaseID:	SPCC584.15c	Length:	594	Species:	Schizosaccharomyces pombe

Alignment Length:	549	Identity:	114/549 - (20%)
Similarity:	189/549 - (34%)	Gaps:	133/549 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 TGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQWRIR-RHGKAVAIQNPKKRSKHQYSGREDYIA 82
            |...::|.|:::::...:::.|||::||.:...|... ||.      :|..|.:.|.....|  .
pombe    37 TSARLSGIVVLSVSSPIRVKNIKLRLSGRSFVCWADESRHA------SPGNRIRRQVVQILD--K 93

  Fly    83 STTYLMGSEQGSNFNMDAGTYTYTFACPIPSHCPSSFEGAYG-HIRY-----LAKVT-------- 133
            |.::|..:|...  .:|.|.|.|.|...:|...|.|.||..| ||.|     |.:.|
pombe    94 SWSFLAPNESAK--VIDQGNYEYPFYYELPPDIPDSIEGIPGCHIIYTLTASLERATQPPTNLET 156

  Fly   134 --------FLKPGASNRTHNVG--------------------------------FTVLKLLDLNQ 158
                    .:.|.:.:..|:|.                                :.:||.||:.:
pombe   157 ALQFRVIRTIPPNSLDLMHSVSVSDIWPLKVNYETSIPSKVYAIGSEIPVNITLYPLLKGLDVGK 221

  Fly   159 ETKMLREPA----SNEAVEHFCLMHTKPVQLKVTL----QQQGYVPGQFMLIHAHVRNDSSSDCR 215
            .|.:|:|..    :::|....|....|...:|.|:    ....|...|.|:.......:.:.||.
pombe   222 VTLVLKEYCTLFITSKAYSSTCRKEFKRALVKKTIPGLPMVDDYWQDQIMVKIPDSLGECTQDCD 286

  Fly   216 KLLIMLH--LRATYTADTP-----SLRTTSEKIMLVKRECGPVAHNAQRTYTETLRIPATAPTCE 273
            ...|.:|  ||.:.:...|     .||.:....:::    .||...|:.|        ....|.:
pombe   287 LNCIRVHHKLRLSISLLNPDGHVSELRNSLPLSLVI----SPVMFGARPT--------EGVFTGD 339

  Fly   274 HLSKV---VRVSYEVRVVAVMNW---LMANPRLIIPVTIGNVPLATAVSGPDFLP-------TNA 325
            |.|.|   :..||:..|..|: |   ...||:|....|..|:   :..:..||.|       :|.
pombe   340 HNSYVNENILPSYDKHVFDVL-WDGIPSENPQLQSGFTTPNL---SRRNSSDFGPNSPVNIHSNP 400

  Fly   326 FPSGSSLPADLPCTSTRAMELAQMAASGVSNSGYEMAEDLEDFELPEDG---------------- 374
            .|.....|:. |.:::.|......:...:|:...:|...:.....|..|
pombe   401 VPISGQQPSS-PASNSNANFFFGSSPQSMSSEQTDMMSPITSPLAPFSGVTRRAARTRANSASSV 464

  Fly   375 -DDELEAAD-DFVPDLPPPTYEQAMFMTTDIADTDANTVSEASRFTPRYPVFDVDTFQSPPPNPP 437
             :.:|:... |.:..||.||...:.......|.|  ..|.|.|:..|.|......|...|....|
pombe   465 FNSQLQPLQTDLLSPLPSPTSSNSRLPRVRSACT--LNVQELSKIPPYYEAHSAFTNVLPLDGLP 527

  Fly   438 QKKRRRRRRRPADPGQSKQQPEKQPVESP 466
               |.....||:.|.:|.:.|......:|
pombe   528 ---RYEEATRPSSPTESVEIPSNTTTIAP 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	41/192 (21%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	32/145 (22%)
SPCC584.15c	NP_588220.1	Arrestin_N	41..166	CDD:304627	33/134 (25%)
SPCC584.15c	NP_588220.1	Arrestin_C	183..324	CDD:214976	24/144 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	52	1.000	Domainoid score	I3293
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910