DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10086 and arrd-8

DIOPT Version :9

Sequence 1:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_496568.1	Gene:	arrd-8 / 189457	WormBaseID:	WBGene00012467	Length:	364	Species:	Caenorhabditis elegans

Alignment Length:	418	Identity:	85/418 - (20%)
Similarity:	154/418 - (36%)	Gaps:	94/418 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 MITFDQNEHGTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQW-------RIRRHGKAVAI 63
            :|.|| :....|..||.:.||:.:..........:|:.|.|..:..|       |..|||:..
Worm     7 LIEFD-HPAAVYSPGQNVAGKLTIRNRNALNALALKICIHGDIETLWRKFENKGRYDRHGRWY-- 68

  Fly    64 QNPKKRSKH-QYSGREDYIASTTYLMGSEQGSNFNMDAGTYTYTFACPIPSHCPSSFEGAYGHIR 127
                :.|:| .|:.:.:.:........|.:.:|..:..|...:.|...:|::.|.||||.:|::|
Worm    69 ----RSSEHINYTSKINVLEGIAQPWSSIENANNKIPGGVNIFPFLFQLPANLPPSFEGTHGNVR 129

  Fly   128 YLAKVTFLKPGASNRTHNVGFTVLKLLDLNQETKMLREPASNEAVEHFCLMHTKPVQLKVTLQQQ 192
            |...|...:|...|......|:|:.::|||...|.: .|....:.:|..|...|.|::|:::.:.
Worm   130 YSVHVELDRPWRMNVEAKRVFSVIPVIDLNSIPKTI-NPMIVSSCKHSGLFSNKEVKVKISIPKS 193

  Fly   193 GYVPGQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTA-----------------DTPSLRTTSEK 240
            ||:||:.:.:.|.::|.:......:...|.....|.|                 :..:.:||..|
Worm   194 GYIPGETIQVSALIQNHTKKPIYSIKAKLEQHVHYQAQQENSHLFPEEHCHKHCEHKTAQTTMSK 258

  Fly   241 IMLVKRECG-PVAHNAQRTYTETLRIPATAP---TCEHLSKVVRVSYEVRVVAVMNWLMANPRLI 301
               |::.|. ....|:|      :.:|...|   .....:.::.|.|.:.|....|..:   |..
Worm   259 ---VEKSCHVEFCSNSQ------INVPLVLPNQLVPSFRTGIIEVDYCIIVDIGENKKL---RCE 311

  Fly   302 IPVTIGNVPLATAVSGPDFLPTNAFPSGSSLPADLPCTSTRAMELAQMAASGVSNSGYEMAEDLE 366
            :|:|:|.:|:........:..|.|.|.                                    .|
Worm   312 LPITVGTIPIGVFTRPIAYSITEAPPK------------------------------------YE 340

  Fly   367 DFELPEDGDDELEAADDFVPDLPPPTYE 394
            :|.         :..:|.....|||.||
Worm   341 NFS---------QIVEDSQASAPPPEYE 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	38/158 (24%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	28/149 (19%)
arrd-8	NP_496568.1	Arrestin_N	6..159	CDD:334019	38/158 (24%)
arrd-8	NP_496568.1	Arrestin_C	180..320	CDD:214976	29/151 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164590
Domainoid	1	1.000	95	1.000	Domainoid score	I4648
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H119234
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		mtm4733
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.850