DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10086 and AgaP_AGAP001894

DIOPT Version :9

Sequence 1:	NP_649736.3	Gene:	CG10086 / 40920	FlyBaseID:	FBgn0037517	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	XP_321170.4	Gene:	AgaP_AGAP001894 / 1281230	VectorBaseID:	AGAP001894	Length:	423	Species:	Anopheles gambiae

Alignment Length:	451	Identity:	124/451 - (27%)
Similarity:	214/451 - (47%)	Gaps:	50/451 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KNCMITFDQNEHGTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQW-----RIRRHGKAVA 62
            |:|.|..| |.:.||:.||.:.|:|....:..||:|||.::.:|.|:.:|     :...:||
Mosquito     4 KDCTIELD-NPYNTYYAGQTVNGRVTFTFDSPKKIRGIVIKFAGEAETKWSETETKTDPNGK--- 64

  Fly    63 IQNPKKRSKHQYSGREDYIASTTYLMGSEQGSNFNMDAGTYTYTFACPIPSHCPSSFEGAYGHIR 127
                :..|....:|:|:|.....||:|.:..:...:.||.:||.|.|.:|...||||||.:|.:|
Mosquito    65 ----QYESTTNLTGQEEYFQIQYYLLGGKNAAESELPAGMHTYPFTCALPPTLPSSFEGEWGFVR 125

  Fly   128 YLAKVTFLKPGASNRTHNVGFTVLKLLDLNQETKMLREPASNEAVEHFCLM--HTKPVQLKVTLQ 190
            |..|||..:|...::...:.|||:..:|||...: :::|...|..:.||..  .:.|:.|.|.:.
Mosquito   126 YTVKVTLDRPWKFDQDIKMAFTVISPVDLNLNPR-VKDPFKLELEKKFCCFCCASGPLSLIVHVP 189

  Fly   191 QQGYVPGQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSEKIMLVKRECGPVAHNA 255
            ..|:|.||.:.:.....|.|:....|:.|.|.....:...||...|..:|.::.....|||....
Mosquito   190 VTGFVSGQSVPVTIECDNASNVGVEKITINLRKLLAFHVHTPRRETKRKKELVTTISMGPVEAGN 254

  Fly   256 QRTYTETLRIPATAPTCEHLSKVVRVSYEVRVVAVMNWLMANPRLIIPVTIGNVPLATAVSGPDF 320
            .:|:.:.|:||...|:......::.|.|:::|||..:.:.||....||:.:|.|||.:..:.|.:
Mosquito   255 SQTWQQFLQIPPLPPSNLVNCGIIDVDYDIKVVAEASGMHANLDGNIPIVLGTVPLESFQAPPPY 319

  Fly   321 LPTNAFPSGSSL------PADLPCTSTRAMELAQMAASGVSNS-GYEMAEDLEDFELPEDGDDEL 378
              |:..|..|.:      |:.||   |:.:..|...::|...: |:.:            ||::.
Mosquito   320 --TDNPPVSSDIIATETDPSMLP---TQPVSPASPPSNGAGGALGWNV------------GDNKA 367

  Fly   379 EAADDFVPDLPPPTYEQAMFMTTDIA---DTDANTVSEASRFTPRYPVFDVDTFQSPPPNP 436
                  .|::||||:.:..:....|:   |::...:.....:.||||.: ..|..:|||.|
Mosquito   368 ------YPNIPPPTFAETSYKAPTISGKNDSEFTRIVGGIEYAPRYPTY-AFTPSAPPPPP 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:278754	51/156 (33%)
CG10086	NP_649736.3	Arrestin_C	179..308	CDD:280848	33/128 (26%)
AgaP_AGAP001894	XP_321170.4	Arrestin_N	6..155	CDD:278754	51/156 (33%)
AgaP_AGAP001894	XP_321170.4	Arrestin_C	179..307	CDD:280848	33/127 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46400
OrthoDB	1	1.010	-	-		D110793at6960
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X122
TreeFam	0	0.000	Not matched by this tool.
	6	5.830