Protein Alignment CG10086 and Arrdc3

DIOPT Version :10

• Sequence 1: NP_649736.3
• Gene: CG10086 / 40920
• FlyBaseID: FBgn0037517
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001036056.1
• Gene: Arrdc3 / 105171
• MGIID: 2145242
• Length: 414
• Species: Mus musculus
• Alignment Length: 486
• Identity: 108/486 - (22%)
• Similarity: 190/486 - (39%)
• Gaps: 113/486 - (23%)

  Fly     3 KNCMITFD---QNEHGTYFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQW-RIRRHGKAVA- 62
            |:..|:||   .:....|.:|..::|:|.:.:....:::.:|:...|:|:.:| ..|..|...|
Mouse     7 KSLTISFDCLNDSNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAGSNTAY 71

  Fly    63 IQNPKKRSKHQYSGREDYIASTTYLMG-------SEQGSNFNMDAGTYTYTFACPIP-SHCPSSF 119
            .||        |:...:|......|:|       ||:|.: .:.:|.:.|.|:..:| :...:||
Mouse    72 TQN--------YTEEVEYFNHKDILIGHERDDDNSEEGFH-TIHSGRHEYAFSFELPQTPLATSF 127

  Fly   120 EGAYGHIRYLAKVTFLKPGASNRTHNVGFTVLKLLDLNQETKMLREPASNEAVEHFC--LMHTKP 182
            ||.:|.:||..|....:|..........|||.:.:|:|  |..|..|.:....:..|  ...:.|
Mouse   128 EGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDIN--TPSLLSPQAGTKEKTLCCWFCTSGP 190

  Fly   183 VQLKVTLQQQGYVPGQFMLIHAHVRNDSSSDCRKLLIMLHLRATYTADTPSLRTTSEKIMLVKRE 247
            :.|...::::||.||:.:.|.|.:.|.||........:...:|.|...  .::...:.:..::.|
Mouse   191 ISLSAKIERKGYTPGESIQIFAEIENCSSRMVVPKAAIYQTQAFYAKG--KMKEVKQLVANLRGE 253

  Fly   248 CGPVAHNAQRTYT---ETLRIPATAPTCEHLSKVVRVSYE----VRVVAVMNWLMANPRLIIPVT 305
                :.::.:|.|   :.|:||..:|:....| ::||.|.    |.:...|:.|::     :|:.
Mouse   254 ----SLSSGKTETWNGKLLKIPPVSPSILDCS-IIRVEYSLMVYVDIPGAMDLLLS-----LPLV 308

  Fly   306 IGNVPL------ATAVSGPDFLPTN----AFPSGSSLP---ADLPCTSTRAMELAQMAASGVSNS 357
            ||.:||      .::||....:..|    |.|.....|   |::.....|...||.:.|
Mouse   309 IGTIPLHPFGSRTSSVSSQCSMSMNWLALALPERPEAPPSYAEVVTEEQRRNNLAPVGA------ 367

  Fly   358 GYEMAEDLEDFELPEDGDDELEAADDFVPDLPPPTYEQAMFMTTDIADTDANTVSEASRFTPRYP 422
                   .:|||....|  .|.|.......||||.|.
Mouse   368 -------CDDFERALQG--PLFAYIQEFRFLPPPLYS---------------------------- 395

  Fly   423 VFDVDTFQSPPPNPPQKKRRRRRRRPADPGQ 453
              ::|      |||.|..    ..||:.|.:
Mouse   396 --EID------PNPDQSS----EDRPSCPSR 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:425619	40/164 (24%)
		Arrestin_C	180..311	CDD:214976	30/137 (22%)
Arrdc3	NP_001036056.1	Arrestin_N	22..165	CDD:425619	37/151 (25%)
		Arrestin_C	187..314	CDD:214976	30/138 (22%)
		PPxY motif 1. /evidence=ECO:0000305	346..349		1/2 (50%)
		PPxY motif 2. /evidence=ECO:0000305	391..394		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	393..414		9/60 (15%)