Protein Alignment CG10086 and txnip

DIOPT Version :10

• Sequence 1: NP_649736.3
• Gene: CG10086 / 40920
• FlyBaseID: FBgn0037517
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: XP_002938510.2
• Gene: txnip / 100492126
• XenbaseID: XB-GENE-968442
• Length: 388
• Species: Xenopus tropicalis
• Alignment Length: 450
• Identity: 89/450 - (19%)
• Similarity: 163/450 - (36%)
• Gaps: 141/450 - (31%)

  Fly    17 YFTGQVITGKVIVNLNKTKKLRGIKLQISGYAQAQWRIRRHGKAVAIQNPKKRSKHQYSGREDYI 81
            |..|:.:||||:|.:.:..::..:::...|.|:..|.          ||.|:..        :|:
 Frog    21 YCGGEKVTGKVLVEVAEVTRVTAVRVLACGVAKVLWS----------QNCKQEM--------EYL 67

  Fly    82 ASTTYLMGSEQ-----GSNFNMDAGTYTYTFACPIP-SHCPSSFEGAYGHIRYLAKVTFLKPGAS 140
            .....|...||     ||........|.|.|...:| ....|||:|.||.::|..|....:|...
 Frog    68 RFEDTLQMEEQPTDSDGSVIMRPGNFYEYKFGFELPQGPLGSSFKGKYGSVKYWVKAFLDRPSHP 132

  Fly   141 NRTHNVGFTVLKLLDLNQETKMLREPASNEAVEHFCLMHTKP--VQLKVTLQQQGYVPGQFMLIH 203
            .:.....|.|..  .:|.:|..|..|.|.:..:....|....  :.:...:.::|:..|:.:.|.
 Frog   133 PQEAQKHFQVED--SVNVDTPDLMSPVSGKKYKKMTCMFIPDGHISMSACINRKGFCEGEDICIS 195

  Fly   204 AHVRNDSSSDCRKLLI---MLHLRATYTADTPSLRTTSEKIMLVKRECGPVAHNAQRTYTE---- 261
            |    |..:.|.::::   .:..:.||.|:       .:..:..::.|....::.....|:
 Frog   196 A----DFENTCSRIVVPKAAIISKHTYLAN-------GQTKVFTQKLCSVRGNHIISGMTDSWRG 249

  Fly   262 -TLRIPATAPT---CEHLSKVVRVSYEVRVVA--------VMNWLMANPRLIIPVTIGNVPLATA 314
             ::|:|...|:   |    .::||.|.:.|..        ::|         :|:.||:
 Frog   250 KSIRVPKIKPSILGC----NILRVEYSLLVYVSVPGAKKIILN---------LPLVIGS------ 295

  Fly   315 VSGPDFLPTNAFPSGSSLPADLPCTSTRAMELAQMAASGVS------------NSGYEMAEDLED 367
                         |.|.:       ::|...:|..|:|.:|            ..||   .|:
 Frog   296 -------------SSSGM-------NSRTSSMASQASSEMSWIELNIPGTPEAPPGY---LDI-- 335

  Fly   368 FELPEDGD---------DELEAADD-----FVPD---LPPPTYEQAMFMTTDIADTDANT 410
              :|||..         |:|:.|.|     :.|:   :|||||.:        .|.:.||
 Frog   336 --VPEDHRLESPTTPLLDDLDGACDSPIFMYAPEFKYMPPPTYTE--------VDVNKNT 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10086	NP_649736.3	Arrestin_N	5..157	CDD:425619	34/145 (23%)
		Arrestin_C	180..311	CDD:214976	23/151 (15%)
txnip	XP_002938510.2	Arrestin_N	10..142	CDD:451447	33/138 (24%)
		Arrestin_C	172..296	CDD:214976	23/166 (14%)
		Periplasmic_Binding_Protein_Type_2	<336..>370	CDD:473866	8/33 (24%)