DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and zgc:123217

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_001032480.1	Gene:	zgc:123217 / 641414	ZFINID:	ZDB-GENE-051113-188	Length:	326	Species:	Danio rerio

Alignment Length:	266	Identity:	77/266 - (28%)
Similarity:	136/266 - (51%)	Gaps:	29/266 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 KCGPHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLINNRYVLTAAHCVIGAVETE 191
            :||....:.::..|.|.....:.|...:.| :||.    .|||:||::::|:|||||:|   .|.
Zfish    27 ECGVAPLNTRIVGGTDAPAGSWPWQVSIHY-NNRH----ICGGTLIHSQWVMTAAHCII---NTN 83

  Fly   192 VGHLTTVRLGEYDTSKDVDCIDDICNQPILQLGIEQATVHPQYDPANKNRIHDIALLRLDRPVVL 256
            : ::.|:.||....|..|      .|...:::||:....||.::.:..|  :||:|::|.:||..
Zfish    84 I-NVWTLYLGRQTQSTSV------ANPNEVKVGIQSIIDHPSFNNSLLN--NDISLMKLSQPVNF 139

  Fly   257 NEYIQPVCLPLVSTRMAINTGELLVVSGWGR----TTTARKSTIKQRLDLPVNDHDYCARKFATR 317
            :.||:|:|  |.:.......|.....:|||.    .......|: |::.:||..:..|:.::.:.
Zfish   140 SLYIRPIC--LAANNSIFYNGTSCWATGWGNIGKDQALPAPQTL-QQVQIPVVANSLCSTEYESV 201

  Fly   318 NIHLISSQLCVGGEFYRDSCDGDSGGPLM-RRGFDQAWYQEGVVSFGNR--CGLEGWPGVYTRVA 379
            |...|:.|:...|:..:.:|.||||||.. ::|  ..|.|.|:.|:|..  |.:..:|.||:||:
Zfish   202 NNATITPQMICAGKANKGTCQGDSGGPFQCKQG--SVWIQAGITSYGTSAGCAVGAYPDVYSRVS 264

  Fly   380 DYMDWI 385
            ::..||
Zfish   265 EFQSWI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	73/255 (29%)
		Tryp_SPc	137..388	CDD:238113	75/256 (29%)
zgc:123217	NP_001032480.1	Tryp_SPc	36..270	CDD:214473	73/255 (29%)
zgc:123217	NP_001032480.1	Tryp_SPc	37..273	CDD:238113	75/256 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910