DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and si:dkeyp-93a5.3

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	XP_021326347.1	Gene:	si:dkeyp-93a5.3 / 571565	ZFINID:	ZDB-GENE-131127-100	Length:	328	Species:	Danio rerio

Alignment Length:	287	Identity:	88/287 - (30%)
Similarity:	128/287 - (44%)	Gaps:	58/287 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 CG-PHSFSN-KVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLINNRYVLTAAHCVIGAVET 190
            || |:...| ::..|.:.....:.||..|:     ||....||||||||::|||||||::....:
Zfish    25 CGRPNPTLNPRIVGGVNATHGAWPWMVSLQ-----GRYGHFCGGSLINNQWVLTAAHCIVDQTPS 84

  Fly   191 EVGHLTTVRLGEYDT-SKDVDCIDDICNQPILQLGIEQATVHPQYDPANKNRIHDIALLRLDRPV 254
            .:    .|.||::.: ..||:.|...         |.....||.|  :|..:.:|||||:|...|
Zfish    85 SI----IVYLGKWRSYVADVNSISRT---------IRHIIPHPSY--SNITKDNDIALLQLTSTV 134

  Fly   255 VLNEYIQPVCLPLVSTRMAINTGELLVVSGW------------GRTTTA---RKSTIKQRLDLPV 304
            ...:||:|:||...::.....|...  |:||            ||||.:   ....|.|..:|.|
Zfish   135 QYTDYIKPICLADENSNFPRGTNSW--VAGWGDIGVLGTGGIRGRTTVSVPLPHPGILQEAELKV 197

  Fly   305 NDHDYCARKFATRNI---HLISSQLCV----GGEFYRDSCDGDSGGPLMRRGFDQAWYQEGVVSF 362
            ..:..|      .||   .:..:.:|.    ||   :.:..||||||||.:  ...|.|.||:|.
Zfish   198 YSNADC------NNICHGRITPNMICAGTRPGG---KATFSGDSGGPLMTK--CSVWVQAGVLSH 251

  Fly   363 GNRCGLEGWPGVYTRVADYMDWIVETI 389
            |..|.....|.|:.||::|..||...:
Zfish   252 GYGCAQPNLPEVFIRVSEYKQWITGNV 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	82/271 (30%)
		Tryp_SPc	137..388	CDD:238113	84/273 (31%)
si:dkeyp-93a5.3	XP_021326347.1	Tryp_SPc	36..274	CDD:238113	82/270 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910