DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and masp2

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_001116330.1	Gene:	masp2 / 560277	ZFINID:	ZDB-GENE-060130-154	Length:	684	Species:	Danio rerio

Alignment Length:	278	Identity:	91/278 - (32%)
Similarity:	146/278 - (52%)	Gaps:	35/278 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 PKCG-PHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLINNRYVLTAAHCVIGAVE 189
            |.|| |....:||..|.:...:|..|..::    ..|.:.:. |.||:::.:|||||| |:.:.|
Zfish   424 PICGQPELKLSKVIGGENAEKNEIPWQVMI----RMGTKFIG-GASLLSDGWVLTAAH-VVKSFE 482

  Fly   190 TEVGHLTTVRLGEYDTSKDVDCIDDICNQPILQLGIEQAT-VHPQYDPANKNRIHDIALLRLDRP 253
            ....  ..:|:|   |.|..|      |:.:  :||.|.. :||||...|.|..|||||::|:..
Zfish   483 DSAN--LQLRMG---TVKHHD------NEAV--VGIPQKIFIHPQYHHDNVNFNHDIALIKLEYK 534

  Fly   254 VVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRT---TTARKSTIKQRLDLPVNDHDYCARKF- 314
            |.:::.:.|||||....|..:...::..|||||.:   |.|..|...:.:.|||::.:.|..|:
Zfish   535 VPVSKAVMPVCLPGREERFVLKANDVGKVSGWGVSNINTPALFSGNLKYVHLPVSNFNDCKTKYD 599

  Fly   315 ----ATRNIHLISSQLCVG-GEFYRDSCDGDSGGPLMRRGFD---QAWYQEGVVSFGNRCGLEGW 371
                :...:.:..:.:|.| .:..:|||.||||||.  ..||   ::|:..|:||:|:.|...|:
Zfish   600 STVTSKGKLVVTENMICAGFSQGGKDSCQGDSGGPF--AFFDKQSKSWFIGGIVSWGHGCAQAGY 662

  Fly   372 PGVYTRVADYMDWIVETI 389
            .||||:|::|:.||.|.:
Zfish   663 YGVYTKVSNYLSWIEEVM 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	84/261 (32%)
		Tryp_SPc	137..388	CDD:238113	85/263 (32%)
masp2	NP_001116330.1	CUB	24..130	CDD:214483
		EGF_CA	134..176	CDD:214542
		CUB	180..289	CDD:278839
		CCP	296..357	CDD:214478
		CCP	362..410	CDD:153056
		Tryp_SPc	435..676	CDD:214473	84/261 (32%)
		Tryp_SPc	436..679	CDD:238113	85/263 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910