Protein Alignment Sp7 and Cfd

DIOPT Version :10

• Sequence 1: NP_649734.2
• Gene: Sp7 / 40918
• FlyBaseID: FBgn0037515
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 225
• Identity: 74/225 - (32%)
• Similarity: 111/225 - (49%)
• Gaps: 32/225 - (14%)

  Fly   167 CGGSLINNRYVLTAAHCVIGAVETEVGHLTTVRLGEYDTSKDVDCIDDICNQPILQL-GIEQATV 230
            |||:|::.::||:||||:.|..:.||   ..|.||.:..|..         :|...| .::...:
  Rat    51 CGGTLVDEQWVLSAAHCMDGVTKDEV---VQVLLGAHSLSSP---------EPYKHLYDVQSVVL 103

  Fly   231 HPQYDPANKNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRTTTA-RKS 294
            ||...|.:..  .|:.|.:|.....|..:::|  |||......:..|.|..|:|||..|.| |:.
  Rat   104 HPGSRPDSVE--DDLMLFKLSHNASLGPHVRP--LPLQREDREVKPGTLCDVAGWGVVTHAGRRP 164

  Fly   295 TIKQRLDLPVNDHDYCARKFATRNIH---LISSQLCVGGEFYRDSCDGDSGGPLMRRGFDQAWYQ 356
            .:.|:|.:.:.|.:.|    ..|..|   :..:.:|.... .||:|.|||||||:..  |..
  Rat   165 DVLQQLTVSIMDRNTC----NLRTYHDGAITKNMMCAESN-RRDTCRGDSGGPLVCG--DAV--- 219

  Fly   357 EGVVSFGNR-CGLEGWPGVYTRVADYMDWI 385
            |.||::|:| ||....|||:||||.|:.||
  Rat   220 EAVVTWGSRVCGNRRKPGVFTRVATYVPWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:463440
		Tryp_SPc	137..388	CDD:238113	74/225 (33%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	74/225 (33%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/3 (33%)