Protein Alignment Sp7 and ACR

DIOPT Version :10

• Sequence 1: NP_649734.2
• Gene: Sp7 / 40918
• FlyBaseID: FBgn0037515
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 84/297 - (28%)
• Similarity: 129/297 - (43%)
• Gaps: 53/297 - (17%)

  Fly   113 DGQAGLGNLLPSPPKCGPHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLINNRYV 177
            ||..||  .....|:.|.     ::..|.......:.||..|:.......|..:|||||:|:|:|
Human    26 DGPCGL--RFRQNPQGGV-----RIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWV 83

  Fly   178 LTAAHC------------VIGAVETEVGHLTTVRLGEYDTSKDVDCIDDICNQPILQLGIEQATV 230
            ||||||            |.||.|...|:...|:                  .|:.:..:|:..:
Human    84 LTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVK------------------APLQERYVEKIII 130

  Fly   231 HPQYDPANKNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSGWG--RTTTARK 293
            |.:|:.|.:.  :||||:.:..|:....:|.|.|||.....:. ...:...|:|||  .....|.
Human   131 HEKYNSATEG--NDIALVEITPPISCGRFIGPGCLPHFKAGLP-RGSQSCWVAGWGYIEEKAPRP 192

  Fly   294 STIKQRLDLPVNDHDYCARKFATR--NIHLISSQLCVG---GEFYRDSCDGDSGGPLM-RRGFDQ 352
            |:|.....:.:.|.|.|.   :|:  |..:..:.:|.|   |:.  |:|.|||||||| :...:.
Human   193 SSILMEARVDLIDLDLCN---STQWYNGRVQPTNVCAGYPVGKI--DTCQGDSGGPLMCKDSKES 252

  Fly   353 AWYQEGVVSFGNRCGLEGWPGVYTRVADYMDWIVETI 389
            |:...|:.|:|..|.....||:||....|::||...|
Human   253 AYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKI 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:463440
		Tryp_SPc	137..388	CDD:238113	77/270 (29%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	75/268 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421