DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and zgc:92313

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_001002596.1	Gene:	zgc:92313 / 436869	ZFINID:	ZDB-GENE-040718-339	Length:	309	Species:	Danio rerio

Alignment Length:	276	Identity:	84/276 - (30%)
Similarity:	128/276 - (46%)	Gaps:	46/276 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 KCGPHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELS-CGGSLINNRYVLTAAHCVIGAVET 190
            :||.....|::..|:..|...:.|.     ||.:|.:... |||::|:..:||:||||.....:.
Zfish    25 ECGRPPMINRIVGGSSAADGAWPWQ-----VDIQGEKSKHVCGGTIISENWVLSAAHCFPNPNDI 84

  Fly   191 EVGHLTTVRLGEY--------DTSKDVDCIDDICNQPILQLGIEQATVHPQYDPANKNRIHDIAL 247
            . |:|  :..|..        :||..:       ::.::.||.    ..||..       .||||
Zfish    85 S-GYL--IYAGRQQLNGWNPDETSHRI-------SRVVVPLGY----TDPQLG-------QDIAL 128

  Fly   248 LRLDRPVVLNEYIQPVCLPLVSTRMAINTGEL-LVVSGWG--RTTTARKST-IKQRLDLPVNDHD 308
            :.|..|.|..|.|||||||..:...   |.:: .:::|||  |...|.:.. ..|.:.:|:.|..
Zfish   129 VELATPFVYTERIQPVCLPYANVEF---TSDMRCMITGWGDIREGVALQGVGPLQEVQVPIIDSQ 190

  Fly   309 YCARKF---ATRNIHLISSQLCVG-GEFYRDSCDGDSGGPLMRRGFDQAWYQEGVVSFGNRCGLE 369
            .|...|   .|.||.:....:|.| .:..:|||.|||||||..:..|.:|.|.|:||||..|...
Zfish   191 ICQDMFLTNPTENIDIRPDMMCAGFQQGGKDSCQGDSGGPLACQISDGSWVQAGIVSFGLGCAEA 255

  Fly   370 GWPGVYTRVADYMDWI 385
            ..||||.:|:.:.::|
Zfish   256 NRPGVYAKVSSFTNFI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	80/265 (30%)
		Tryp_SPc	137..388	CDD:238113	81/266 (30%)
zgc:92313	NP_001002596.1	Tryp_SPc	34..271	CDD:214473	80/265 (30%)
zgc:92313	NP_001002596.1	Tryp_SPc	35..274	CDD:238113	81/266 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587315
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840