DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and CG4613

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	109/314 - (34%)
Similarity:	158/314 - (50%)	Gaps:	53/314 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 SFGSQEATSAAPP--PTTTSSSSRGQDGQAGLGNLLPSPPKCGPHSFSNKVYNGNDTAIDEFNWM 151
            |.||...:|:|.|  |.      .|...:|...|...| ..||..:. |::..|.....:::.|:
  Fly    95 SLGSTSLSSSASPVFPL------EGGGAKAFRVNRCAS-CTCGVPNV-NRIVGGTQVRTNKYPWI 151

  Fly   152 ALLEYVDNRGRRELSCGGSLINNRYVLTAAHCVIGAVETEVGHLTTVRLGEYDTSKDVDCIDDIC 216
            |.:    .|| ..|.|||:|||:||||||||||.|.....|    :|||.:.|.|.
  Fly   152 AQI----IRG-TFLFCGGTLINDRYVLTAAHCVHGMDMRGV----SVRLLQLDRSS--------- 198

  Fly   217 NQPILQLGIEQ----ATVHPQYDPANKNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRMAINTG 277
                ..||:.:    |..|..|||.  :.:|||||||||:|:.|.:.::|.|||  |..:.....
  Fly   199 ----THLGVTRSVAFAHAHVGYDPV--SLVHDIALLRLDQPIPLVDTMRPACLP--SNWLQNFDF 255

  Fly   278 ELLVVSGWGRTTT-ARKSTIKQRLDLPVNDHDYCARKFATRNIHLISSQLCVGGEFY-----RDS 336
            :..:|:|||.:.. ...|::.|.:.:|:..:..| |..:.|:: ::.:.:|.|   |     ||:
  Fly   256 QKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQC-RATSYRSM-IVDTMMCAG---YVKTGGRDA 315

  Fly   337 CDGDSGGPLMRRGFDQAWYQEGVVSFGNRCGLEGWPGVYTRVADYMDWIVETIR 390
            |.|||||||:.|  |:.:...||||||..|.....|||||||:.|::||....|
  Fly   316 CQGDSGGPLIVR--DRIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWIAVNTR 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	92/258 (36%)
		Tryp_SPc	137..388	CDD:238113	94/260 (36%)
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	92/258 (36%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	92/257 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457378
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	4	3.940