DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and CG8172

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_001097235.2	Gene:	CG8172 / 35905	FlyBaseID:	FBgn0033362	Length:	561	Species:	Drosophila melanogaster

Alignment Length:	322	Identity:	112/322 - (34%)
Similarity:	167/322 - (51%)	Gaps:	55/322 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 TSAAPPPTTTSSSSRG-------------------QDGQAGLGNLLPSP-PKCGP-HSFSNKVYN 139
            ::.||||.....:::.                   ..|..|..:....| |.||. ::.||::..
  Fly   254 SAGAPPPHEPLPNAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDASYRPVPGCGEVYTRSNRIVG 318

  Fly   140 GNDTAIDEFNW-MALLEYVDNRG--RRELSCGGSLINNRYVLTAAHCVIGAVETEVGHLTTVRLG 201
            |:.|......| :||::    .|  .|:|||||:||:||:|:||||||.....:.:    .:|||
  Fly   319 GHSTGFGSHPWQVALIK----SGFLTRKLSCGGALISNRWVITAAHCVASTPNSNM----KIRLG 375

  Fly   202 EYDTSKDVDCIDDICNQPILQLGIEQATVHPQYDPANKNRIHDIALLRLDRPVVLNEYIQPVCLP 266
            |:|.....:.::.      .:.|||:..|||.|:||  :.::|:||:||||.||..::|.|||||
  Fly   376 EWDVRGQEERLNH------EEYGIERKEVHPHYNPA--DFVNDVALIRLDRNVVYKQHIIPVCLP 432

  Fly   267 LVSTRMAINTGELLVVSGWGRTTTARKS--TIKQRLDLPVNDHDYCARKF--ATRNIHLISSQLC 327
            ..:|::   ||::..|:|||||...:.:  ::.|.:|:.|..:|.|.|.|  |.|...:....||
  Fly   433 PSTTKL---TGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLC 494

  Fly   328 VGGEFY----RDSCDGDSGGPLMRRGFDQAWYQEGVVSFGNRCGLEGWPGVYTRVADYMDWI 385
            .|   |    ||||.|||||||... .|......|:||:|..||.|..|||||.:..::.||
  Fly   495 AG---YKDGGRDSCQGDSGGPLTLT-MDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWI 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	98/259 (38%)
		Tryp_SPc	137..388	CDD:238113	100/260 (38%)
CG8172	NP_001097235.2	Tryp_SPc	315..552	CDD:214473	98/259 (38%)
CG8172	NP_001097235.2	Tryp_SPc	316..555	CDD:238113	100/260 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457346
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	3	2.840