DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sp7 and Ser6

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_523426.1	Gene:	Ser6 / 33073	FlyBaseID:	FBgn0011834	Length:	259	Species:	Drosophila melanogaster

Alignment Length:	279	Identity:	88/279 - (31%)
Similarity:	125/279 - (44%)	Gaps:	63/279 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 PPKCGPHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLINNRYVLTAAHCVIGAVE 189
            |.:..|...:.:|..|.|...::|.....|.   |.|..  |||||::...|:|||||||   ..
  Fly    20 PVQSAPGKLNGRVVGGEDAVKNQFPHQVSLR---NAGSH--SCGGSILTRTYILTAAHCV---SN 76

  Fly   190 TEVGHLT--------TVRLGEYDTSKDVDCIDDICNQPILQLGIEQATVHPQYDPANKNRIHDIA 246
            .:|.|:.        |:|.|..|.         .....::|  :.:..||.:|.    |.::|:|
  Fly    77 EDVNHVITPIAAERFTIRAGSNDR---------FSGGVLVQ--VAEVIVHEEYG----NFLNDVA 126

  Fly   247 LLRLDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRTTTARKSTIKQRLDLPVNDHDYCA 311
            ||||:.|::|:..|||:.||.|.|...::    :|:|||||        ||.:.||| ....|..
  Fly   127 LLRLESPLILSASIQPIDLPTVDTPADVD----VVISGWGR--------IKHQGDLP-RYLQYNT 178

  Fly   312 RKFATRN--IHLI----SSQLCVGGEFYRDSCDGDSGGPLMRRGFDQAWYQE---GVVSF-GNRC 366
            .|..||.  ..||    ..:||:..:....:|:||||||        |.|..   ||..| .:.|
  Fly   179 LKSITRQQCEELIDFGFEGELCLLHQVDNGACNGDSGGP--------AVYNNQLVGVAGFVVDGC 235

  Fly   367 GLEGWPGVYTRVADYMDWI 385
            | ..:|..|.||..:.|||
  Fly   236 G-STYPDGYARVFYFKDWI 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	84/266 (32%)
		Tryp_SPc	137..388	CDD:238113	86/267 (32%)
Ser6	NP_523426.1	Tryp_SPc	31..253	CDD:214473	84/266 (32%)
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	86/267 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457358
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840