Protein Alignment Sp7 and HP

DIOPT Version :10

• Sequence 1: NP_649734.2
• Gene: Sp7 / 40918
• FlyBaseID: FBgn0037515
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_005134.1
• Gene: HP / 3240
• HGNCID: 5141
• Length: 406
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 80/301 - (26%)
• Similarity: 127/301 - (42%)
• Gaps: 64/301 - (21%)

  Fly   118 LGNLLPS-PPKCG-PHSFSN---KVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLINNRYV 177
            :|:.||. ...|| |.:.:|   ::..|:..|...|.|.|.:.     ....|:.|.:|||.:::
Human   138 VGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMV-----SHHNLTTGATLINEQWL 197

  Fly   178 LTAAHCVIGAVETEVGHLTTVRLGEYDTSKDVDCIDDICNQPILQL--------GIEQATVHPQY 234
            ||.|..:.      :.|      .|..|:||:        .|.|.|        .||:..:||.|
Human   198 LTTAKNLF------LNH------SENATAKDI--------APTLTLYVGKKQLVEIEKVVLHPNY 242

  Fly   235 DPANKNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRTTTARKSTIKQR 299
            ...      ||.|::|.:.|.:||.:.|:|||   ::.....|.:..||||||....:.:...:.
Human   243 SQV------DIGLIKLKQKVSVNERVMPICLP---SKDYAEVGRVGYVSGWGRNANFKFTDHLKY 298

  Fly   300 LDLPVNDHDYCARKFATRNIH--------------LISSQLCVG-GEFYRDSCDGDSGGPLMRRG 349
            :.|||.|.|.|.|.:....:.              |.....|.| .::..|:|.||:|.......
Human   299 VMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHD 363

  Fly   350 FDQ-AWYQEGVVSFGNRCGLEGWPGVYTRVADYMDWIVETI 389
            .:: .||..|::||...|.:..: |||.:|....||:.:||
Human   364 LEEDTWYATGILSFDKSCAVAEY-GVYVKVTSIQDWVQKTI 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:463440
		Tryp_SPc	137..388	CDD:238113	71/274 (26%)
HP	NP_005134.1	CCP	33..87	CDD:153056
		CCP	92..146	CDD:153056	3/7 (43%)
		Tryp_SPc	162..402	CDD:238113	71/274 (26%)