Protein Alignment Sp7 and TMPRSS11E

DIOPT Version :10

• Sequence 1: NP_649734.2
• Gene: Sp7 / 40918
• FlyBaseID: FBgn0037515
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_054777.2
• Gene: TMPRSS11E / 28983
• HGNCID: 24465
• Length: 423
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 97/376 - (25%)
• Similarity: 147/376 - (39%)
• Gaps: 77/376 - (20%)

  Fly    48 QSLLSVIQQS-YVSPEDRTFLRN-----SQCLDGVGRQPYVCCTSDRSFGSQEATSAAPPPTTTS 106
            |.|.|:::.: |.||....|:::     ||...||.....:.|    .|.|.|............
Human    81 QRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLLIC----RFHSTEDPETVDKIVQLV 141

  Fly   107 SSSRGQDGQAGLGNLLPSPPKCGPHSF----------------------------SNKVYNGNDT 143
            ...:.||.        ..|||..|||.                            |.::..|.:.
Human   142 LHEKLQDA--------VGPPKVDPHSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEV 198

  Fly   144 AIDEFNWMALLEYVDNRGRRELSCGGSLINNRYVLTAAHCVIGAVETEVGHLTTVR-LGEYDTSK 207
            ...|:.|.|.|:: |...|    ||.:|||..::::||||           .||.: ...:..|.
Human   199 EEGEWPWQASLQW-DGSHR----CGATLINATWLVSAAHC-----------FTTYKNPARWTASF 247

  Fly   208 DVDCIDDICNQPILQLGIEQATVHPQYDPANKNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRM 272
            .|........:.:.::.:.:...||.:|       :||:|..|..||.....:..||||..|  .
Human   248 GVTIKPSKMKRGLRRIIVHEKYKHPSHD-------YDISLAELSSPVPYTNAVHRVCLPDAS--Y 303

  Fly   273 AINTGELLVVSGWG--RTTTARKSTIKQRLDLPVNDHDYCARKFATRNIHLISSQLCVGG-EFYR 334
            ....|:::.|:|:|  :.....::.::| ..:.:.|...|....| .|..:....||.|. |...
Human   304 EFQPGDVMFVTGFGALKNDGYSQNHLRQ-AQVTLIDATTCNEPQA-YNDAITPRMLCAGSLEGKT 366

  Fly   335 DSCDGDSGGPLMRRGFDQAWYQEGVVSFGNRCGLEGWPGVYTRVADYMDWI 385
            |:|.|||||||:.......||..|:||:|:.|.....|||||||....|||
Human   367 DACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:463440	11/41 (27%)
		Tryp_SPc	137..388	CDD:238113	73/253 (29%)
TMPRSS11E	NP_054777.2	SEA	51..147	CDD:460188	15/69 (22%)
		Tryp_SPc	192..420	CDD:238113	73/253 (29%)