DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and try-1

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_494910.2	Gene:	try-1 / 173856	WormBaseID:	WBGene00006619	Length:	293	Species:	Caenorhabditis elegans

Alignment Length:	300	Identity:	85/300 - (28%)
Similarity:	130/300 - (43%)	Gaps:	87/300 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 CGPHS-------------------FSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLIN 173
            ||.||                   ..:::..|::::...:.|  .::.:...|...  ||||||:
Worm    30 CGLHSTNVELAQTRSAQEPADYVTLDHRLIGGSESSPHSWPW--TVQLLSRLGHHR--CGGSLID 90

  Fly   174 NRYVLTAAHCV------------IGAVETEVGHLTTVRLGEYDTSKDVDCIDDICNQPILQLGIE 226
            ..:|||||||.            :|      ||    |.|.....:                 :.
Worm    91 PNFVLTAAHCFAKDRRPTSYSVRVG------GH----RSGSGSPHR-----------------VT 128

  Fly   227 QATVHPQYD---PANKNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRT 288
            ..::||.|:   |::    :|.|::|:..||..:...:|:|||.:.   |:. ..|.||:|||.|
Worm   129 AVSIHPWYNIGFPSS----YDFAIMRIHPPVNTSTTARPICLPSLP---AVE-NRLCVVTGWGST 185

  Fly   289 ---TTARKSTIKQRLDLPVNDHDYCAR--KFATRNIHLISSQLCVGGEFYR-DSCDGDSGGPLM- 346
               ::....|::: :.:|:....:|:.  .:..| ||| .|.||.|..:.: |||.||||||||
Worm   186 IEGSSLSAPTLRE-IHVPLLSTLFCSSLPNYIGR-IHL-PSMLCAGYSYGKIDSCQGDSGGPLMC 247

  Fly   347 -RRGFDQAWYQEGVVSFGNRCGLEGWPGVYTRVADYMDWI 385
             |.|.   |...||||:|..|...|.||||..|.....||
Worm   248 ARDGH---WELTGVVSWGIGCARPGMPGVYGNVHSASTWI 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	79/271 (29%)
		Tryp_SPc	137..388	CDD:238113	80/271 (30%)
try-1	NP_494910.2	Tryp_SPc	59..285	CDD:238113	80/270 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910