DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and Tpsb2

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_034911.3	Gene:	Tpsb2 / 17229	MGIID:	96942	Length:	276	Species:	Mus musculus

Alignment Length:	286	Identity:	88/286 - (30%)
Similarity:	135/286 - (47%)	Gaps:	50/286 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 LGNLLPSPPKCGPHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELS-----CGGSLINNRYV 177
            |.:|:.|.|:  |.:....:..|::.:..::.|...|.:       :|:     ||||||:.::|
Mouse    15 LASLVYSAPR--PANQRVGIVGGHEASESKWPWQVSLRF-------KLNYWIHFCGGSLIHPQWV 70

  Fly   178 LTAAHCVIGAVETEVGHLTTVRLGE----YDTSKDVDCIDDICNQPILQLGIEQATVHPQYDPAN 238
            |||||||...:::.  .|..|:|.|    |.        |.:       |.:.:..|||.|..|.
Mouse    71 LTAAHCVGPHIKSP--QLFRVQLREQYLYYG--------DQL-------LSLNRIVVHPHYYTAE 118

  Fly   239 KNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRTTTAR----KSTIKQR 299
            ...  |:|||.|:.||.::.::.|:.||..|.  ....|....|:|||......    ...:||
Mouse   119 GGA--DVALLELEVPVNVSTHLHPISLPPASE--TFPPGTSCWVTGWGDIDNDEPLPPPYPLKQ- 178

  Fly   300 LDLPVNDHDYCARKFAT-----RNIHLISSQLCVGGEFYRDSCDGDSGGPLMRRGFDQAWYQEGV 359
            :.:|:.::..|.||:.|     .:..::...:...|...||||.|||||||:.: ....|.|.||
Mouse   179 VKVPIVENSLCDRKYHTGLYTGDDFPIVHDGMLCAGNTRRDSCQGDSGGPLVCK-VKGTWLQAGV 242

  Fly   360 VSFGNRCGLEGWPGVYTRVADYMDWI 385
            ||:|..|.....||:||||..|:|||
Mouse   243 VSWGEGCAQPNKPGIYTRVTYYLDWI 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	81/266 (30%)
		Tryp_SPc	137..388	CDD:238113	83/267 (31%)
Tpsb2	NP_034911.3	Tryp_SPc	32..270	CDD:238113	83/267 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842839
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840