DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and Tpsab1

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_112464.4	Gene:	Tpsab1 / 100503895	MGIID:	96943	Length:	273	Species:	Mus musculus

Alignment Length:	306	Identity:	97/306 - (31%)
Similarity:	132/306 - (43%)	Gaps:	76/306 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 AAPPPTTTSSSSRGQDGQAGLGNLLPSPPKCGPHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGR 162
            |||.|..|.....|  ||...||..|....          ...|||     .||..
Mouse    18 AAPGPAMTREGIVG--GQEAHGNKWPWQVS----------LRANDT-----YWMHF--------- 56

  Fly   163 RELSCGGSLINNRYVLTAAHCVIGAVETEVGHLTTVRLGEYDTSKDVDCIDDICNQPILQ----L 223
                ||||||:.::|||||||    |..:|.....||:             .:..|.:..    :
Mouse    57 ----CGGSLIHPQWVLTAAHC----VGPDVADPNKVRV-------------QLRKQYLYYHDHLM 100

  Fly   224 GIEQATVHPQY----DPANKNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSG 284
            .:.|...||.:    |.|      |||||:|..||.:::|:.||.||..|.  ...:|.|..|:|
Mouse   101 TVSQIITHPDFYIVQDGA------DIALLKLTNPVNISDYVHPVPLPPASE--TFPSGTLCWVTG 157

  Fly   285 WGR----TTTARKSTIKQRLDLPVNDHDYCARKF-----ATRNIHLI-SSQLCVGGEFYRDSCDG 339
            ||.    ........:|: :.:|:.::..|..|:     ...|:|:: ...||.|.|.: |||.|
Mouse   158 WGNIDNGVNLPPPFPLKE-VQVPIIENHLCDLKYHKGLITGDNVHIVRDDMLCAGNEGH-DSCQG 220

  Fly   340 DSGGPLMRRGFDQAWYQEGVVSFGNRCGLEGWPGVYTRVADYMDWI 385
            ||||||:.: .:..|.|.||||:|..|.....||:||||..|:|||
Mouse   221 DSGGPLVCK-VEDTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	84/266 (32%)
		Tryp_SPc	137..388	CDD:238113	86/267 (32%)
Tpsab1	NP_112464.4	Tryp_SPc	29..266	CDD:238113	92/295 (31%)
Tpsab1	NP_112464.4	Tryp_SPc	29..265	CDD:214473	90/293 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842838
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840