DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and LOC100004427

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	XP_005163955.1	Gene:	LOC100004427 / 100004427	-ID:	-	Length:	302	Species:	Danio rerio

Alignment Length:	266	Identity:	75/266 - (28%)
Similarity:	117/266 - (43%)	Gaps:	45/266 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 CGPHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLINNRYVLTAAHCV----IGAV 188
            ||....:.|:..|.:.....:.|.|.:.:   :...:..|.||||:.|:|||||.|.    :..|
Zfish    27 CGRAPLNTKIVGGLNATEGSWPWQASINF---KSTGQFFCSGSLISERWVLTAASCFQRINVSDV 88

  Fly   189 ETEVGHLTTVRLGEYDTSKDVDCIDDICNQPILQLGIEQATVHPQYDPANKNRIHDIALLRLDRP 253
            ...:|.|||.....|:..:.|           :|:.:.:                ||||::|...
Zfish    89 VIYLGRLTTNGSNPYEIPRTV-----------IQVSVTE----------------DIALVQLSSS 126

  Fly   254 VVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRT--TTARKSTIKQRLDLPVNDHDYCARKFAT 316
            |...:||:||||....:.....|...  |:|||.|  |....|.:.:.::.|:.::..|:.   .
Zfish   127 VTFTDYIRPVCLAAAGSVFVDGTESW--VTGWGSTSSTNVILSDMLKEVEAPIVNNIECSN---I 186

  Fly   317 RNIHLISSQLCVG--GEFYRDSCDGDSGGPLMRRGFDQAWYQEGVVSFGNRCGLEGWPGVYTRVA 379
            ..|..:.:.:|.|  .|..:..|..|.|.||:.|...| |.|.|||.| ..||..|:|.:|.||:
Zfish   187 NGITNLDNVICAGFVNETGKAPCWEDFGSPLVTRQGSQ-WIQSGVVVF-TFCGQNGFPTLYARVS 249

  Fly   380 DYMDWI 385
            :|.:||
Zfish   250 EYEEWI 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	71/256 (28%)
		Tryp_SPc	137..388	CDD:238113	72/257 (28%)
LOC100004427	XP_005163955.1	Tryp_SPc	35..255	CDD:214473	71/256 (28%)
LOC100004427	XP_005163955.1	Tryp_SPc	36..257	CDD:238113	72/257 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587295
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930