DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp7 and si:dkey-16l2.17

DIOPT Version :9

Sequence 1:	NP_649734.2	Gene:	Sp7 / 40918	FlyBaseID:	FBgn0037515	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	XP_001341498.1	Gene:	si:dkey-16l2.17 / 100001520	ZFINID:	ZDB-GENE-141212-262	Length:	305	Species:	Danio rerio

Alignment Length:	279	Identity:	81/279 - (29%)
Similarity:	125/279 - (44%)	Gaps:	44/279 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 CGPHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLINNRYVLTAAHCV-----IGA 187
            ||......::..|.:.:...:.|...::    .|.....||||:|...:||:||||.     :.|
Zfish    23 CGRPPLGKRIVGGVEASPGSWPWQVDIQ----MGSNGHVCGGSIIAKNWVLSAAHCFPNPSEVSA 83

  Fly   188 VETEVG-HLTTVRLGEYDTSKDVDCIDDICNQPILQLGIEQATVHPQ--YDPANKNRIHDIALLR 249
            ....:| ||    |..|:..:.|..:              |..|.|:  .||...   .|:||::
Zfish    84 YTLYMGRHL----LNGYNQFEKVSYV--------------QRVVIPEGYTDPQGG---RDVALVQ 127

  Fly   250 LDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRT---TTARKSTIKQRLDLPVNDHDYCA 311
            |..||...:.|||||||...  ...|:|.|..|:|||..   .:...:...:.:::|:.|...|.
Zfish   128 LRAPVSWTDRIQPVCLPFAD--FQFNSGTLCYVTGWGHKQEGVSLTGAAALREVEVPIIDQSSCQ 190

  Fly   312 RKFA-----TRNIHLISSQLCVG-GEFYRDSCDGDSGGPLMRRGFDQAWYQEGVVSFGNRCGLEG 370
            ..:.     :..:.::|..:|.| .|..:|||.|||||||:....:..|.|.||||||..|..:.
Zfish   191 FMYQILSSDSSTVDILSDMICAGYKEGGKDSCQGDSGGPLVCPVGNGTWIQAGVVSFGLGCAQKN 255

  Fly   371 WPGVYTRVADYMDWIVETI 389
            .||:|:||:.:...|..|:
Zfish   256 RPGIYSRVSSFEKLIRTTV 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp7	NP_649734.2	CLIP	31..84	CDD:288855
		Tryp_SPc	136..385	CDD:214473	77/265 (29%)
		Tryp_SPc	137..388	CDD:238113	78/267 (29%)
si:dkey-16l2.17	XP_001341498.1	Tryp_SPc	32..273	CDD:238113	78/267 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587316
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840