Protein Alignment pyd3 and NIT1

DIOPT Version :10

• Sequence 1: NP_649732.1
• Gene: pyd3 / 40916
• FlyBaseID: FBgn0037513
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: XP_005245271.1
• Gene: NIT1 / 4817
• HGNCID: 7828
• Length: 344
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 86/358 - (24%)
• Similarity: 137/358 - (38%)
• Gaps: 64/358 - (17%)

  Fly    45 KDIAEQNGFDI-------KGYRF-------------TAREEQTRKRRIVRVGAIQNS-------I 82
            |.::|:.||.:       ..:||             :....|.|.|.:    ||.:|       .
Human     7 KRLSEERGFSLMLGFITRPPHRFLSLLCPGLRIPQLSVLCAQPRPRAM----AISSSSCELPLVA 67

  Fly    83 VIPTTAPIEKQREAIWNKVKTMIKAAAEAGCNIVCTQEAWTMPFAFCTREKFPWCEFAEEAENGP 147
            |...|:..:||:.  :.....:::.||..|..:....||    |.|..|:.......:|.. .|.
Human    68 VCQVTSTPDKQQN--FKTCAELVREAARLGACLAFLPEA----FDFIARDPAETLHLSEPL-GGK 125

  Fly   148 TTKMLAELAKAYNM-VIIHSILER--DMEHGETIWNTAVVISNSGRYLGKHRKNH-----IPRVG 204
            ..:...:||:...: :.:....||  |.|..:.|:|..|::::.|..:..:||.|     ||..|
Human   126 LLEEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQG 190

  Fly   205 DFNESTYYMEGNTGHPVFETEFGKLAVNICYGRHHPQNWMMFGLNGAEIVFNPSATIGRLSEPL- 268
            ...||...|.|.:......|..||:.:.:||....|:..:.....||||:..||| .|.::.|.
Human   191 PMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSA-FGSITGPAH 254

  Fly   269 WSIEARNAAIANSYFTVPINRVGTEQFPNEYTSGDGNKAHKEFGPFYGSSYVAAPDGSRTPSLSR 333
            |.:..|..||....:.|...:.|               .|.|....||.|.|..|.|:.....|
Human   255 WEVLLRARAIETQCYVVAAAQCG---------------RHHEKRASYGHSMVVDPWGTVVARCS- 303

  Fly   334 DKDGLLVVELDLNLCRQVKDFWGFRMTQRVPLY 366
            :..||.:..:|||..||::........:|..||
Human   304 EGPGLCLARIDLNYLRQLRRHLPVFQHRRPDLY 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pyd3	NP_649732.1	ML_beta-AS	9..372	CDD:143611	86/358 (24%)
NIT1	XP_005245271.1	nit	65..332	CDD:143596	71/290 (24%)