DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pyd3 and upb1

DIOPT Version :9

Sequence 1:	NP_649732.1	Gene:	pyd3 / 40916	FlyBaseID:	FBgn0037513	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_955910.1	Gene:	upb1 / 322660	ZFINID:	ZDB-GENE-030131-1380	Length:	384	Species:	Danio rerio

Alignment Length:	385	Identity:	252/385 - (65%)
Similarity:	299/385 - (77%)	Gaps:	1/385 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAFELKNLNDCLEKHLPPDELKEVKRILYGVEEDQTLELPTSAKDIAEQNGFDIKGYRFTAREE 65
            ||..:.::|...||.|||..||||.:|:|:| :|.:.|:||.||.|.|.|..||:|||.|.|..|
Zfish     1 MSGKDFESLEKVLEAHLPEAELKEARRLLFG-KELKKLDLPRSAIDAAGQQDFDLKGYVFEASPE 64

  Fly    66 QTRKRRIVRVGAIQNSIVIPTTAPIEKQREAIWNKVKTMIKAAAEAGCNIVCTQEAWTMPFAFCT 130
            |.|..|:||||.|||.||:||.||:.:|..|:..:|..|::.||..|.||||.||||||||||||
Zfish    65 QLRPPRMVRVGLIQNKIVLPTDAPVLEQITALHKRVGEMVEVAAMCGVNIVCFQEAWTMPFAFCT 129

  Fly   131 REKFPWCEFAEEAENGPTTKMLAELAKAYNMVIIHSILERDMEHGETIWNTAVVISNSGRYLGKH 195
            ||:.||.||||.||:|.||:...:|||.:|||::..|||||..||.|:||||||:||:|..|||.
Zfish   130 REREPWTEFAESAEDGLTTRFCIQLAKKHNMVVVSPILERDEIHGGTLWNTAVVVSNNGNVLGKT 194

  Fly   196 RKNHIPRVGDFNESTYYMEGNTGHPVFETEFGKLAVNICYGRHHPQNWMMFGLNGAEIVFNPSAT 260
            ||||||||||||||||||||||||.||:|:|||:|||||||||||.||:|:.:|||||:||||||
Zfish   195 RKNHIPRVGDFNESTYYMEGNTGHRVFQTQFGKIAVNICYGRHHPLNWLMYSVNGAEIIFNPSAT 259

  Fly   261 IGRLSEPLWSIEARNAAIANSYFTVPINRVGTEQFPNEYTSGDGNKAHKEFGPFYGSSYVAAPDG 325
            :|.||||:|.||||||||||..||..|||||||.|.||:|||||.|||.:||.||||||:|||||
Zfish   260 VGLLSEPMWPIEARNAAIANHCFTCAINRVGTEYFKNEFTSGDGKKAHHDFGHFYGSSYMAAPDG 324

  Fly   326 SRTPSLSRDKDGLLVVELDLNLCRQVKDFWGFRMTQRVPLYAESFKKASEHGFKPQIIKE 385
            ||||.|||.:|||||.||||||.|||.|.|.|:||.|..:|||..|||.:|.|||.::|:
Zfish   325 SRTPGLSRTRDGLLVAELDLNLNRQVADKWNFKMTGRYEMYAEELKKAIQHDFKPNVMKD 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pyd3	NP_649732.1	PLN00202	9..385	CDD:177792	249/375 (66%)
pyd3	NP_649732.1	ML_beta-AS	9..372	CDD:143611	242/362 (67%)
upb1	NP_955910.1	PLN00202	6..384	CDD:177792	249/378 (66%)
upb1	NP_955910.1	ML_beta-AS	9..371	CDD:143611	242/362 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580888
Domainoid	1	1.000	418	1.000	Domainoid score	I629
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9471
Inparanoid	1	1.050	518	1.000	Inparanoid score	I1234
OMA	1	1.010	-	-		QHG55618
OrthoDB	1	1.010	-	-		D300920at33208
OrthoFinder	1	1.000	-	-		FOG0006264
OrthoInspector	1	1.000	-	-		oto41198
orthoMCL	1	0.900	-	-		OOG6_102400
Panther	1	1.100	-	-	LDO	PTHR43674
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3768
SonicParanoid	1	1.000	-	-		X4546
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800