DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pyd3 and Upb1

DIOPT Version :9

Sequence 1:	NP_649732.1	Gene:	pyd3 / 40916	FlyBaseID:	FBgn0037513	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_446297.1	Gene:	Upb1 / 116593	RGDID:	620091	Length:	393	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	240/385 - (62%)
Similarity:	300/385 - (77%)	Gaps:	1/385 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAFELKNLNDCLEKHLPPDELKEVKRILYGVEEDQTLELPTSAKDIAEQNGFDIKGYRFTAREE 65
            |:..|.::|..|||||||||:|.:||||||| ::.:.|:||..|.:.|.:..|::|||.|.|.:|
  Rat     1 MAGPEWQSLEQCLEKHLPPDDLSQVKRILYG-KQTRNLDLPRKALEAASERNFELKGYAFGAAKE 64

  Fly    66 QTRKRRIVRVGAIQNSIVIPTTAPIEKQREAIWNKVKTMIKAAAEAGCNIVCTQEAWTMPFAFCT 130
            |.|..:|||||.:||.|.:||:||:.:|..|:..:::.:.:.||..|.||:|.||||.|||||||
  Rat    65 QQRCPQIVRVGLVQNRIPLPTSAPVAEQVSALHKRIEEIAEVAAMCGVNIICFQEAWNMPFAFCT 129

  Fly   131 REKFPWCEFAEEAENGPTTKMLAELAKAYNMVIIHSILERDMEHGETIWNTAVVISNSGRYLGKH 195
            |||.||.||||.||:|.||:...:|||.:|||:|..|||||.:||..:|||||||||||..:||.
  Rat   130 REKLPWTEFAESAEDGLTTRFCQKLAKKHNMVVISPILERDRDHGGVLWNTAVVISNSGLVMGKT 194

  Fly   196 RKNHIPRVGDFNESTYYMEGNTGHPVFETEFGKLAVNICYGRHHPQNWMMFGLNGAEIVFNPSAT 260
            |||||||||||||||||||||.|||||:|:||::|||||||||||.||:|:.:|||||:||||||
  Rat   195 RKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSVNGAEIIFNPSAT 259

  Fly   261 IGRLSEPLWSIEARNAAIANSYFTVPINRVGTEQFPNEYTSGDGNKAHKEFGPFYGSSYVAAPDG 325
            ||.|||.:|.||||||||||..||..:||||.|.:|||:|||||.|||.:.|.||||||||||||
  Rat   260 IGELSESMWPIEARNAAIANHCFTCALNRVGQEHYPNEFTSGDGKKAHHDLGYFYGSSYVAAPDG 324

  Fly   326 SRTPSLSRDKDGLLVVELDLNLCRQVKDFWGFRMTQRVPLYAESFKKASEHGFKPQIIKE 385
            ||||.|||::|||||.||:||||:|:.|||.|:||.|:.:||....:|.:..:.|.|:||
  Rat   325 SRTPGLSRNQDGLLVTELNLNLCQQINDFWTFKMTGRLEMYARELAEAVKPNYSPNIVKE 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pyd3	NP_649732.1	PLN00202	9..385	CDD:177792	236/375 (63%)
pyd3	NP_649732.1	ML_beta-AS	9..372	CDD:143611	233/362 (64%)
Upb1	NP_446297.1	ML_beta-AS	9..371	CDD:143611	233/362 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	412	1.000	Domainoid score	I660
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9471
Inparanoid	1	1.050	514	1.000	Inparanoid score	I1253
OMA	1	1.010	-	-		QHG55618
OrthoDB	1	1.010	-	-		D300920at33208
OrthoFinder	1	1.000	-	-		FOG0006264
OrthoInspector	1	1.000	-	-		oto98040
orthoMCL	1	0.900	-	-		OOG6_102400
Panther	1	1.100	-	-	LDO	PTHR43674
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4546
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980