DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2616 and AT2G46320

DIOPT Version :9

Sequence 1:	NP_001287212.1	Gene:	CG2616 / 40915	FlyBaseID:	FBgn0037512	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_850451.1	Gene:	AT2G46320 / 819240	AraportID:	AT2G46320	Length:	361	Species:	Arabidopsis thaliana

Alignment Length:	382	Identity:	120/382 - (31%)
Similarity:	172/382 - (45%)	Gaps:	72/382 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 DSKSSHRKLLSDPRFQIRPLQQVISACTGAMITACFMTPLDVIKTRMQSQQ-------SPAHKCF 129
            |.||.     |.|...::..::.:||...|.|:|..:.||||:|||:|:|.       |....||
plant     8 DPKSK-----SIPNENLKFGERALSAGGAAFISAVIVNPLDVVKTRLQAQAAGVPYQGSCRLGCF 67

  Fly   130 FYSNGLMDHLFASGPNG----SELASLRQRPQFSSSWDALMKISRHEGLAALWSGLGPTLVSALP 190
            ..::.|:..|.::...|    :..||:....|:..:.|...||.|.||.:.||.|...:|..|:|
plant    68 DTNSTLVHDLRSNSAPGMCRITGSASVCSDNQYKGTLDVFYKIIRQEGFSRLWRGTNASLTLAIP 132

  Fly   191 STIIYFVAYEQFKARYLQIYESHYNKSQEPRHLEIRDTKKSLPSVVPMMSGVTARICAVTVVSPI 255
            :..||...|:.|:    .|.| .:...:.|          ||...||:::|..||..|.....|:
plant   133 TVGIYMPCYDYFR----NIME-EFTTEKSP----------SLTVYVPLVAGTIARSLACISCYPV 182

  Fly   256 ELVRTKMQAQRQTYAQMLQFVRSVVALQGVWG------------------LWRGLRPTILRDVPF 302
            ||.||:|||.:.|...        |.|.|||.                  ||.||...:.|||||
plant   183 ELARTRMQAFKGTQRN--------VKLPGVWKTLVDVVNPVKGSNNGYRMLWTGLGAQLARDVPF 239

  Fly   303 SGIYWPIYESLKQNL--GHGSQPS----FSLSFLAGVMAGTVAAIVTTPFDVVKTHEQIEFGERV 361
            |.|.|.|.|..::::  ..|.:|.    ...:|.||.:||.|||..|.|.||.||..|||.....
plant   240 SAICWSILEPTRRSIQSAMGEEPRAGSIIGANFAAGFVAGAVAAAATCPLDVAKTRRQIEKNTDR 304

  Fly   362 IFTDSPARDFGKKSTFSRLTGIYRTHGVRGLFAGCGPRLLKVAPACAIMISTFEYSK 418
            ..|         .:|...|..|:|..|:||:|:|.|.|:.:..|:.||::|.:|..|
plant   305 AMT---------MTTRQTLAEIWRDGGMRGMFSGAGARVGRAGPSVAIVVSFYEVVK 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2616	NP_001287212.1	Mito_carr	86..207	CDD:278578	39/131 (30%)
		Mito_carr	230..321	CDD:278578	36/110 (33%)
		Mito_carr	321..425	CDD:278578	36/102 (35%)
AT2G46320	NP_850451.1	Mito_carr	17..148	CDD:395101	39/134 (29%)
		Mito_carr	158..255	CDD:395101	36/104 (35%)
		Mito_carr	<286..352	CDD:395101	26/74 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3661
eggNOG	1	0.900	-	-		E1_KOG0761
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6040
Inparanoid	1	1.050	153	1.000	Inparanoid score	I1691
OMA	1	1.010	-	-		QHG53824
OrthoDB	1	1.010	-	-		D1007936at2759
OrthoFinder	1	1.000	-	-		FOG0001594
OrthoInspector	1	1.000	-	-		mtm1053
orthoMCL	1	0.900	-	-		OOG6_101405
Panther	1	1.100	-	-	O	PTHR45760
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1001
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840