Protein Alignment CG2616 and SLC25A28

DIOPT Version :10

• Sequence 1: NP_649731.1
• Gene: CG2616 / 40915
• FlyBaseID: FBgn0037512
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_112489.3
• Gene: SLC25A28 / 81894
• HGNCID: 23472
• Length: 364
• Species: Homo sapiens
• Alignment Length: 443
• Identity: 110/443 - (24%)
• Similarity: 161/443 - (36%)
• Gaps: 97/443 - (21%)

  Fly     1 MSKEDSGASSAEANPAESEISMGRGPRPRSFTGG--GGGGGTGGSGGSGGTSGGNNLKPERSARE 63
            |..|..||......||...   ||.|...:...|  ..|.|.|..||..|.     .:|  ..|:
Human     1 MELEGRGAGGVAGGPAAGP---GRSPGESALLDGWLQRGVGRGAGGGEAGA-----CRP--PVRQ 55

  Fly    64 DDAINRLTDSKSSHRKLLSDPRFQIRP-----LQQVISACTGAMITACFMTPLDVIKTRMQS-QQ 122
            |..               |.|.::..|     ...:::.....::..|.|.|:|.:|||||| |.
Human    56 DPD---------------SGPDYEALPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQP 105

  Fly   123 SPAHKCFFYSNGLMDHLFASGPNGSELASLRQRPQFSSSWDALMKISRHEGLAALWSGLGPTLVS 187
            .||.:   |.|.|                           :||.:|.|.|||.....||..|...
Human   106 DPAAR---YRNVL---------------------------EALWRIIRTEGLWRPMRGLNVTATG 140

  Fly   188 ALPSTIIYFVAYEQFKARYLQIYESHYNKSQEPRHLEIRDTKKSLPSVVPMMSGVTARICAVTVV 252
            |.|:..:||..||:.|.....:.....|.                 .:....:|..|.:.....:
Human   141 AGPAHALYFACYEKLKKTLSDVIHPGGNS-----------------HIANGAAGCVATLLHDAAM 188

  Fly   253 SPIELVRTKMQAQRQTYAQMLQFVRSVVALQGVWGLWRGLRPTILRDVPFSGIYWPIYESLKQNL 317
            :|.|:|:.:||.....|.::...||:|...:|....:|.....:..:|||..|::..||.|:::.
Human   189 NPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHF 253

  Fly   318 GHGSQPSFSLSFLAGVMAGTVAAIVTTPFDVVK----THEQIEFGERVIFTDSPARDFGKKSTFS 378
            ....:.:.|...|:|..||.|||..|||.||.|    |.|.:.....:     .....|..|.|.
Human   254 NPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALNSHI-----TGHITGMASAFR 313

  Fly   379 RLTGIYRTHGVRGLFAGCGPRLLKVAPACAIMISTFEYSKSFFFHYNVRHHNE 431
            .   :|:..||...|.|...|::...|:.||..|.:|     ||.|.:....|
Human   314 T---VYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYE-----FFKYLITKRQE 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2616	NP_649731.1	Mito_carr	86..207	CDD:395101	34/126 (27%)
		Mito_carr	230..321	CDD:395101	20/90 (22%)
		Mito_carr	321..425	CDD:395101	32/107 (30%)
SLC25A28	NP_112489.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		9/29 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..60		7/41 (17%)
		Solcar 1	70..158		33/117 (28%)
		Mito_carr	71..161	CDD:395101	33/119 (28%)
		Solcar 2	168..252		21/100 (21%)
		Mito_carr	169..253	CDD:395101	20/100 (20%)
		Solcar 3	259..352		32/105 (30%)
		Mito_carr	<279..356	CDD:395101	25/89 (28%)