DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2616 and Slc25a40

DIOPT Version :9

Sequence 1:	NP_001287212.1	Gene:	CG2616 / 40915	FlyBaseID:	FBgn0037512	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_001380639.1	Gene:	Slc25a40 / 296813	RGDID:	1308774	Length:	337	Species:	Rattus norvegicus

Alignment Length:	356	Identity:	150/356 - (42%)
Similarity:	216/356 - (60%)	Gaps:	44/356 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 PRFQIRPLQQVISACTGAMITACFMTPLDVIKTRMQSQQS--PAHKCFFYSNGLMDHLFASGPNG 146
            |..|:.||||::::|.||::|:..:|||||:|.|:|:|.:  |..|||.||||||||:... ...
  Rat    10 PTIQVTPLQQMMASCAGAVVTSLMVTPLDVVKIRLQAQNNPFPKGKCFLYSNGLMDHICIC-EEE 73

  Fly   147 SELASLRQRPQFSSSWDALMKISRHEGLAALWSGLGPTLVSALPSTIIYFVAYEQFKARYLQIYE 211
            |:.|..::...|..:.||.:||.|:||:.:|||||.||||.|:|:|:|||..|||.
  Rat    74 SKKAWYKKPGNFHGTLDAFLKIVRNEGIKSLWSGLPPTLVMAVPATVIYFTCYEQL--------- 129

  Fly   212 SHYNKSQEPRHLEIRDTKKSLPSVVPMMSGVTARICAVTVVSPIELVRTKMQAQRQTYAQMLQFV 276
            |.:.|::    |...:|:      :|:::|:.||..|||::||:||:|||||::..:|.::.|.|
  Rat   130 STFLKTK----LGENETR------IPIVAGIVARFGAVTMISPLELIRTKMQSKTFSYKELYQIV 184

  Fly   277 RSVVALQGVWGLWRGLRPTILRDVPFSGIYWPIYESLKQNLGHGS---QPSFSLSFLAGVMAGTV 338
            ...|:..|...||:|..||||||||||.:||..||:|::.|...|   :.:|.::|.||.::|:.
  Rat   185 SMKVSEDGWISLWKGWAPTILRDVPFSAMYWYNYENLRRWLCEKSDLYESTFMINFTAGALSGSF 249

  Fly   339 AAIVTTPFDVVK--------THEQIEFGERVIFTDSPARDFGKKSTFSRLTGIYRTHGVRGLFAG 395
            ||:.|.||||||        |||..:|.|.:           ..||:|.:..|....|..|||.|
  Rat   250 AAVATLPFDVVKTQKQTQLWTHEYCKFPEPL-----------DMSTWSIMKNIVADRGFSGLFTG 303

  Fly   396 CGPRLLKVAPACAIMISTFEYSKSFFFHYNV 426
            ..|||:|:.||||||||::|..|.||...||
  Rat   304 LIPRLVKIVPACAIMISSYELGKGFFQQQNV 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2616	NP_001287212.1	Mito_carr	86..207	CDD:278578	58/122 (48%)
		Mito_carr	230..321	CDD:278578	40/90 (44%)
		Mito_carr	321..425	CDD:278578	45/114 (39%)
Slc25a40	NP_001380639.1	Mito_carr	13..137	CDD:395101	60/137 (44%)
		Solcar 1	14..132		58/127 (46%)
		Solcar 2	140..224		40/89 (45%)
		Mito_carr	146..229	CDD:395101	39/82 (48%)
		Mito_carr	232..330	CDD:395101	43/108 (40%)
		Solcar 3	234..328		42/104 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4669
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6040
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2735
OMA	1	1.010	-	-		QHG53824
OrthoDB	1	1.010	-	-		D1007936at2759
OrthoFinder	1	1.000	-	-		FOG0001594
OrthoInspector	1	1.000	-	-		mtm9100
orthoMCL	1	0.900	-	-		OOG6_101405
Panther	1	1.100	-	-	O	PTHR45760
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1001
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980