Protein Alignment Nlg1 and Ache

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: XP_038945765.1
• Gene: Ache / 83817
• RGDID: 69313
• Length: 616
• Species: Rattus norvegicus
• Alignment Length: 611
• Identity: 204/611 - (33%)
• Similarity: 293/611 - (47%)
• Gaps: 92/611 - (15%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCP 222
            ::|:.|:|.||  |.:...|  .|..|||:|:||.|.|:||||||....||.|:..|.....||.
  Rat    41 VRVRGGQLRGI--RLKAPGG--PVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGILDATTFQNVCY 101

  Fly   223 QKLPDLSP--HGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQS-TPKQYAVLVYLH 284
            |.:..|.|  .|:|..:..|..            ||||||||::.|:..|.| ||    ||::::
  Rat   102 QYVDTLYPGFEGTEMWNPNREL------------SEDCLYLNVWTPYPRPTSPTP----VLIWIY 150

  Fly   285 GESFEWNSG----NPYDGSVLSSYGEVIVVTVNYRLGVLGFLR--PSIDAHNIANYALLDQIAAL 343
            |..|  .||    :.|||..|:.....::|::|||:|..|||.  .|.||.  .|..||||..||
  Rat   151 GGGF--YSGASSLDVYDGRFLAQVEGTVLVSMNYRVGTFGFLALPGSRDAP--GNVGLLDQRLAL 211

  Fly   344 HWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWA--ASNQSL 406
            .|::|||.|||||...|||.|.|.|||.|...::|..:..|||||:|.||:....||  ::.::.
  Rat   212 QWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEAR 276

  Fly   407 QLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDIL----HIPTALTQFSTSLGPIVDGHVI 467
            :....:|..:.||...  ...:|..|:.|||.|..||::    |:....:.|..|..|:|||..:
  Rat   277 RRATLLARLVGCPPGG--AGGNDTELISCLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFL 339

  Fly   468 PNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERDN-----LLRFYMQSRFD 527
            .:.|..::.  |..|....:|.|:.:.|..:.|.     .|:....:||     ..:|....|..
  Rat   340 SDTPEALIN--TGDFQDLQVLVGVVKDEGSYFLV-----YGVPGFSKDNESLISRAQFLAGVRIG 397

  Fly   528 I--RPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMY 590
            :  ..|||..|.:..|.| :.:|....:|  ||.:..::.|..||.|:.|.....|....|.|.|
  Rat   398 VPQASDLAAEAVVLHYTD-WLHPEDPAHL--RDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAY 459

  Fly   591 VFGHNSA--TGP-FAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVK 652
            :|.|.::  |.| :..:||   |.|:.||||.||.     ||.||||:|::.::.:|.|||||.:
  Rat   460 IFEHRASTLTWPLWMGVPH---GYEIEFIFGLPLD-----PSLNYTVEERIFAQRLMKYWTNFAR 516

  Fly   653 TGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPP-TVGYKYRQIYMNFWNKELPD 716
            ||:|..|            .|.....||.:...||.|:::.:.| .|....|.....|||:.||.
  Rat   517 TGDPNDP------------RDSKSPRWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPK 569

  Fly   717 ELNQIA----------AIQEQLQKPG 732
            .|:..|          |..|...:||
  Rat   570 LLSATATEVPCTCPSPAHGEAAPRPG 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	193/577 (33%)
		Aes	<263..>408	CDD:223730	62/153 (41%)
Ache	XP_038945765.1	COesterase	37..563	CDD:395084	193/577 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910