Protein Alignment Nlg1 and Ces1h

DIOPT Version :9

• Sequence 1: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 614
• Identity: 176/614 - (28%)
• Similarity: 278/614 - (45%)
• Gaps: 112/614 - (18%)

  Fly   158 IQVKQGRLMGITRRFQVTSGLRQ-VDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVC 221
            :....|:::|   ::....|..| |..|||:|:|:.|.|:.||.||..|.||..:|.|...||:|
Mouse    26 VNTTHGKVLG---KYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATSYPPMC 87

  Fly   222 P------QKLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTPKQYAVL 280
            .      |.:.||..:..|.: |.|.             ||||||||:|.|.:..::| .:..|:
Mouse    88 SQDAVLGQMVNDLIINNKEKI-RLRF-------------SEDCLYLNVYTPVDLMKNT-NRLPVM 137

  Fly   281 VYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNIANYALLDQIAALHW 345
            |::||........:.|||..||::..|:|||:.|||.:.||.... |.|:..|:..|||:|||||
Mouse   138 VWIHGGGLVVGGASAYDGRTLSAHENVVVVTIQYRLAIWGFFSTG-DEHSRGNWGHLDQLAALHW 201

  Fly   346 IKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVASGLFHRAILMSGSAMSDWAASNQSLQLTM 410
            |::||..||||...||:.|.|.|...|:.|::||:|..||||||..||...:.......:..:|.
Mouse   202 IQDNIANFGGDPGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDASSVTE 266

  Fly   411 QIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQFSTS-----------LGPIVDG 464
            |||....|      :.....|::.|||.:..:::|.|...:..|...           |..::||
Mouse   267 QIAVTAGC------KTTTSAVIVHCLRQKTEEELLEIMQKMNLFKLDAQENTKKNYPFLPTVLDG 325

  Fly   465 HVIPNQPYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGLRENERD-NLLRFYMQSR--- 525
            .|:|..|..::..  ::|:....:.||.:.|...|| .:.:|....:.:.| .::..:::..
Mouse   326 VVLPKAPEAILAE--KNFNTVPYIVGINKQEFGWTL-PMIMEFPPTDVKLDKKVISLFLRKLAYF 387

  Fly   526 FDIRPDLALAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRRNYMY 590
            |:| |:..:...::||....::||     ::|..:|.::.|.....|.:.....|.|.....|||
Mouse   388 FNI-PEDGIPVAIEKYSKGTDDPI-----QNRVWLLQLIGDVMFGIPSVIVSRGHRDAGAPTYMY 446

  Fly   591 VFGH----------NSATGPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMA 645
            .|..          .:.||..        |:|:..:||||:...|.      :.:|..||:.:|.
Mouse   447 EFQSRPSFSSELKPKTVTGDH--------GDEVYSVFGAPILREGS------SEEEINLSKMMMK 497

  Fly   646 YWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFW 710
            :|.||.:.|||         |...|.      .|||:|:: :.||.||.........:...::.|
Mouse   498 FWANFARNGNP---------NGQGLP------HWPEYNQK-KGYLQIGATTQQAQGLKDKEVSLW 546

  Fly   711 NKELPDELNQIAAIQEQLQKPGQEVITGH 739
            .     ||        :.:||.|   |||
Mouse   547 T-----EL--------RAKKPPQ---TGH 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	167/583 (29%)
		Aes	<263..>408	CDD:223730	57/144 (40%)
Ces1h	NP_001357759.1	COesterase	24..546	CDD:365897	167/583 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810